Carboxyebselen | CAS# 153871-75-1 | nitric oxide synthase inhibitor

MedKoo Cat#: 412323 | Name: Carboxyebselen

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Carboxyebselen is a nitric oxide synthase inhibitor.

Chemical Structure

Carboxyebselen

CAS#153871-75-1

Theoretical Analysis

MedKoo Cat#: 412323

Name: Carboxyebselen

CAS#: 153871-75-1

Chemical Formula: C14H9NO3Se

Exact Mass: 318.9748

Molecular Weight: 318.19

Elemental Analysis: C, 52.85; H, 2.85; N, 4.40; O, 15.08; Se, 24.82

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

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Synonym

Carboxyebselen

IUPAC/Chemical Name

2-(4-Carboxyphenyl)-1,2-benzisoselenazol-3(2H)-one

InChi Key

FOEPTYDLLXMPLJ-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H9NO3Se/c16-13-11-3-1-2-4-12(11)19-15(13)10-7-5-9(6-8-10)14(17)18/h1-8H,(H,17,18)

SMILES Code

O=C1N(C2=CC=C(C(O)=O)C=C2)[Se]C3=C1C=CC=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 318.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Hatchett RJ, Gryglewski RJ, Młochowski J, Zembowicz A, Radziszewski W. Carboxyebselen a potent and selective inhibitor of endothelial nitric oxide synthase. J Physiol Pharmacol. 1994 Mar;45(1):55-67. PMID: 7519084. 2: Cai W, Wu J, Xi C, Ashe AJ 3rd, Meyerhoff ME. Carboxyl-ebselen-based layer- by-layer films as potential antithrombotic and antimicrobial coatings. Biomaterials. 2011 Nov;32(31):7774-84. doi: 10.1016/j.biomaterials.2011.06.075. Epub 2011 Jul 26. PMID: 21794909; PMCID: PMC3159861.