MedKoo Cat#: 575406 | Name: Fendiline

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fendiline is a coronary vasodilator that inhibits calcium function in muscle cells in excitation-contraction coupling; proposed as an antiarrhythmic and antianginal agent.

Chemical Structure

Fendiline
Fendiline
CAS#13042-18-7

Theoretical Analysis

MedKoo Cat#: 575406

Name: Fendiline

CAS#: 13042-18-7

Chemical Formula: C23H25N

Exact Mass: 315.1987

Molecular Weight: 315.46

Elemental Analysis: C, 87.57; H, 7.99; N, 4.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Fendiline
IUPAC/Chemical Name
Benzenepropanamine, gamma-phenyl-N-(1-phenylethyl)-
InChi Key
NMKSAYKQLCHXDK-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H25N/c1-19(20-11-5-2-6-12-20)24-18-17-23(21-13-7-3-8-14-21)22-15-9-4-10-16-22/h2-16,19,23-24H,17-18H2,1H3
SMILES Code
CC(NCCC(c1ccccc1)c2ccccc2)c3ccccc3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 315.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Alhothali M, Mathew M, Iyer G, Lawrence HR, Yang S, Chellappan S, Padmanabhan J. Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC. Int J Mol Sci. 2019 May 16;20(10):2423. doi: 10.3390/ijms20102423. PMID: 31100813; PMCID: PMC6567171. 2. Bayer R, Mannhold R. Fendiline: a review of its basic pharmacological and clinical properties. Pharmatherapeutica. 1987;5(2):103-36. PMID: 3310016.