MedKoo Cat#: 463270 | Name: Quoromycin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Quoromycin is a novel antivirulence agent against Vibrio vulnificus, inhibiting the quorum-sensing signaling pathway by controlling the DNA-binding affinity of SmcR and thus effectively alleviating the virulence of V. vulnificus in vitro and in vivo.

Chemical Structure

Quoromycin
Quoromycin
CAS#205514-29-0

Theoretical Analysis

MedKoo Cat#: 463270

Name: Quoromycin

CAS#: 205514-29-0

Chemical Formula: C12H8N2O2S

Exact Mass: 244.0306

Molecular Weight: 244.27

Elemental Analysis: C, 59.01; H, 3.30; N, 11.47; O, 13.10; S, 13.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Quoromycin;
IUPAC/Chemical Name
6-(phenylsulfonyl)nicotinonitrile
InChi Key
WLMRLYWAJRGRKR-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H8N2O2S/c13-8-10-6-7-12(14-9-10)17(15,16)11-4-2-1-3-5-11/h1-7,9H
SMILES Code
N#CC1=CN=C(S(=O)(C2=CC=CC=C2)=O)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 244.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kim SM, Park J, Kim MS, Song H, Jo A, Park H, Kim TS, Choi SH, Park SB. Phenotypic Discovery of an Antivirulence Agent against Vibrio vulnificus via Modulation of Quorum-Sensing Regulator SmcR. ACS Infect Dis. 2020 Oct 21. doi: 10.1021/acsinfecdis.0c00587. Epub ahead of print. PMID: 33086782.