E-2101 | CAS#265667-22-9 | Antispastic

MedKoo Cat#: 463205 | Name: E-2101

Description:

WARNING: This product is for research use only, not for human or veterinary use.

E-2101 is a novel antispastic drug.

Chemical Structure

E-2101

CAS#265667-22-9

Theoretical Analysis

MedKoo Cat#: 463205

Name: E-2101

CAS#: 265667-22-9

Chemical Formula: C24H28FN3O

Exact Mass: 393.2216

Molecular Weight: 393.51

Elemental Analysis: C, 73.26; H, 7.17; F, 4.83; N, 10.68; O, 4.07

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

E-2101; E2101; E 2101;

IUPAC/Chemical Name

2-(1-(1-(2-fluorophenethyl)piperidin-4-yl)-1H-indol-6-yl)-N-methylacetamide

InChi Key

CQEOXWCXSBFJMB-UHFFFAOYSA-N

InChi Code

InChI=1S/C24H28FN3O/c1-26-24(29)17-18-6-7-20-9-15-28(23(20)16-18)21-10-13-27(14-11-21)12-8-19-4-2-3-5-22(19)25/h2-7,9,15-16,21H,8,10-14,17H2,1H3,(H,26,29)

SMILES Code

CNC(Cc(cc1)cc2c1ccn2C3CCN(CC3)CCc4c(F)cccc4)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 393.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kushida I, Ashizawa K. Solid state characterization of E2101, a novel antispastic drug. J Pharm Sci. 2002 Oct;91(10):2193-202. doi: 10.1002/jps.10211. PMID: 12226846. 2: Zhang ZY, King BM, Mollova NN, Wong YN. In vitro interactions between a potential muscle relaxant E2101 and human cytochromes P450. Drug Metab Dispos. 2002 Jul;30(7):805-13. doi: 10.1124/dmd.30.7.805. PMID: 12065439.