Synonym
Albuterol adipate
IUPAC/Chemical Name
4-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol hemiadipate
InChi Key
VNBHFEGZBMWMGV-UHFFFAOYSA-N
InChi Code
1S/2C13H21NO3.C6H10O4/c2*1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;7-5(8)3-1-2-4-6(9)10/h2*4-6,12,14-17H,7-8H2,1-3H3;1-4H2,(H,7,8)(H,9,10)
SMILES Code
c1(cc(CO)c(O)cc1)[C@@H](CNC(C)(C)C)O.C(CCCCC(=O)O)(=O)O.c1(ccc(O)c(CO)c1)[C@@H](O)CNC(C)(C)C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
624.77
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Chen D, Yang M, Zheng N, Xie N, Liu D, Xie C, Yao D. A novel aptasensor for
electrochemical detection of ractopamine, clenbuterol, salbutamol,
phenylethanolamine and procaterol. Biosens Bioelectron. 2016 Jun 15;80:525-31.
doi: 10.1016/j.bios.2016.01.025. Epub 2016 Jan 11. PubMed PMID: 26890828.
2: Wang MY, Zhu W, Ma L, Ma JJ, Zhang DE, Tong ZW, Chen J. Enhanced simultaneous detection of ractopamine and salbutamol--Via electrochemical-facial deposition of MnO2 nanoflowers onto 3D RGO/Ni foam templates. Biosens Bioelectron. 2016 Apr15;78:259-66. doi: 10.1016/j.bios.2015.11.062. Epub 2015 Nov 22. PubMed PMID:26623510.
3: Flores P, Mendes AL, Neto AS. A randomized trial of nebulized 3% hypertonic
saline with salbutamol in the treatment of acute bronchiolitis in hospitalized
infants. Pediatr Pulmonol. 2016 Apr;51(4):418-25. doi: 10.1002/ppul.23306. Epub
2015 Sep 3. PubMed PMID: 26334188.
4: Rodríguez-Ramos F, Andrade-Moreno MÁ, Alfaro-Romero A, Balderas-López JL,
Navarrete A. Gnaphaliin A and gnaphaliin B synergize the relaxant effect of
salbutamol but not of ipratropium in guinea pig trachea. J Pharm Pharmacol. 2016
Apr 7. doi: 10.1111/jphp.12536. [Epub ahead of print] PubMed PMID: 27061296.
5: Andrzejowski P, Carroll W. Salbutamol in paediatrics: pharmacology,
prescribing and controversies. Arch Dis Child Educ Pract Ed. 2016 Apr 8. pii:
edpract-2014-307285. doi: 10.1136/archdischild-2014-307285. [Epub ahead of print] PubMed PMID: 27059284.
