TH1760 is a novel inhibitor against the NUDIX hydrolase NUDT15, sensitizing cells to 6-thioguanine through enhanced accumulation of 6-thio-(d)GTP in nucleic acids.
MedKoo Cat#: 463199
Name: TH1760
CAS#: 2567914-01-4
Chemical Formula: C20H18N4O5S
Exact Mass: 426.0998
Molecular Weight: 426.45
Elemental Analysis: C, 56.33; H, 4.25; N, 13.14; O, 18.76; S, 7.52
The following data is based on the product molecular weight 426.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
