BW 540C | CAS# 83908-32-1 | anti-inflammatory

MedKoo Cat#: 412174 | Name: BW 540C

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BW 540C is an anti-inflammatory.

Chemical Structure

BW 540C

CAS#83908-32-1

Theoretical Analysis

MedKoo Cat#: 412174

Name: BW 540C

CAS#: 83908-32-1

Chemical Formula: C11H12F3N3

Exact Mass: 243.0983

Molecular Weight: 243.23

Elemental Analysis: C, 54.32; H, 4.97; F, 23.43; N, 17.28

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

BW 540C; BW540-C; BW 540-C; BW-540-C

IUPAC/Chemical Name

1H-Pyrazol-3-amine, 4,5-dihydro-N-methyl-1-(3-(trifluoromethyl)phenyl)-

InChi Key

MWRJSSGQTGTSKH-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H12F3N3/c1-15-10-5-6-17(16-10)9-4-2-3-8(7-9)11(12,13)14/h2-4,7H,5-6H2,1H3,(H,15,16)

SMILES Code

FC(C1=CC(N2N=C(NC)CC2)=CC=C1)(F)F

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 243.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: van Wauwe JP, Goossens JG. Arabinogalactan- and dextran-induced ear inflammation in mice: differential inhibition by H1-antihistamines, 5-HT- serotonin antagonists and lipoxygenase blockers. Agents Actions. 1989 Aug;28(1-2):78-82. doi: 10.1007/BF02022984. PMID: 2476925. 2: Reynolds CH. Inactivation of soybean lipoxygenase by lipoxygenase inhibitors in the presence of 15-hydroperoxyeicosatetraenoic acid. Biochem Pharmacol. 1988 Dec 1;37(23):4531-7. doi: 10.1016/0006-2952(88)90669-7. PMID: 3144281. 3: Read NG, Astbury PJ, Morgan RJ, Parsons DN, Port CJ. Induction and exacerbation of hyaline droplet formation in the proximal tubular cells of the kidneys from male rats receiving a variety of pharmacological agents. Toxicology. 1988 Nov 14;52(1-2):81-101. doi: 10.1016/0300-483x(88)90198-9. PMID: 3188035. 4: Higgins AJ, Lees P, Sedgwick AD. Actions of BW540C in an equine model of acute inflammation: a preliminary study. Vet Q. 1987 Apr;9(2):103-10. doi: 10.1080/01652176.1987.9694086. PMID: 3039716. 5: Higgins AJ, Lees P, Sedgwick AD, Buick AR, Churchus R. Use of a novel non- steroidal anti-inflammatory drug in the horse. Equine Vet J. 1987 Jan;19(1):60-6. doi: 10.1111/j.2042-3306.1987.tb02584.x. PMID: 3691462. 6: Dawson B, Follenfant RL, Higgs GA, Schneider C, Gibson JR. The effect of BW 540C, a novel anti-inflammatory agent, on ultraviolet-induced physical and histological changes in guinea-pig skin. Br J Dermatol. 1985 Jul;113 Suppl 28:137-40. doi: 10.1111/j.1365-2133.1985.tb15644.x. PMID: 4015980.