MedKoo Cat#: 555858 | Name: VUN65671
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

VUN65671is a Potent Entry Inhibitor of Ebola and Marburg Virus Infections. VUN65671 was reported in Journal of Medicinal Chemistry (2020), 63(13), 7211-7225. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

VUN65671
VUN65671
CAS# 2479465-67-1

Theoretical Analysis

MedKoo Cat#: 555858

Name: VUN65671

CAS#: 2479465-67-1

Chemical Formula: C25H30F3N3O2

Exact Mass: 461.2290

Molecular Weight: 461.53

Elemental Analysis: C, 65.06; H, 6.55; F, 12.35; N, 9.10; O, 6.93

Price and Availability

Size Price Availability Quantity
100mg USD 1,250.00 2 Weeks
1g USD 4,650.00 2 Weeks
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Related CAS #
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Synonym
VUN65671; VUN-65671; VUN 65671; EBOV/MARV-IN-1
IUPAC/Chemical Name
Benzamide,N-[4-(4-methyl-1-piperidinyl)-3-(trifluoromethyl)phenyl]-4-(4-morpholinylmethyl)-
InChi Key
VVJSZYWIEBDKTC-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H30F3N3O2/c1-18-8-10-31(11-9-18)23-7-6-21(16-22(23)25(26,27)28)29-24(32)20-4-2-19(3-5-20)17-30-12-14-33-15-13-30/h2-7,16,18H,8-15,17H2,1H3,(H,29,32)
SMILES Code
O=C(NC1=CC=C(N2CCC(C)CC2)C(C(F)(F)F)=C1)C3=CC=C(CN4CCOCC4)C=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 461.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Gaisina IN, Peet NP, Wong L, Schafer AM, Cheng H, Anantpadma M, Davey RA, Thatcher GRJ, Rong L. Discovery and Structural Optimization of 4-(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections. J Med Chem. 2020 Jul 9;63(13):7211-7225. doi: 10.1021/acs.jmedchem.0c00463. Epub 2020 Jun 17. PMID: 32490678; PMCID: PMC7671190.