MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 412111 | Name: Pentetate Calcium Trisodium (salt)

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pentetate Calcium Trisodium is the trisodium salt form of calcium diethylene triamine pentaacetate that acts as an iron chelating agent.

Chemical Structure

Pentetate Calcium Trisodium (salt)
Pentetate Calcium Trisodium (salt)
CAS#12111-24-9 (salt)

Theoretical Analysis

MedKoo Cat#: 412111

Name: Pentetate Calcium Trisodium (salt)

CAS#: 12111-24-9 (salt)

Chemical Formula: C14H18CaN3Na3O10

Exact Mass:

Molecular Weight: 497.35

Elemental Analysis: C, 33.81; H, 3.65; Ca, 8.06; N, 8.45; Na, 13.87; O, 32.17

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
12111-24-9 (salt) 2531-75-1 (free base)
Synonym
Pentetate Calcium Trisodium; Ba2797; Ba-2797; Ba 2797
IUPAC/Chemical Name
Acetic acid, ((carboxymethylimino)bis(ethylenenitrilo))tetra-, calcium trisodium salt
InChi Key
AYFCVLSUPGCQKD-UHFFFAOYSA-I
InChi Code
InChI=1S/C14H23N3O10.Ca.3Na/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;;;;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);;;;/q;+2;3*+1/p-5
SMILES Code
O=C(CN(CCN(CC([O-])=O)CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O)[O-].[Ca+2].[Na+].[Na+].[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Pentetate Calcium Trisodium is the trisodium salt form of calcium diethylene triamine pentaacetate (Ca-DTPA or pentetate calcium) with chelating activity. Upon administration, Ca-DTPA loses the Ca ion to form stable chelates with metal ions because DTPA has a higher affinity for heavy metal ions than for Ca ions. Specifically, this agent is able to bind to and form strong complexes with radioactive plutonium, americium, and cerium after internal contamination with any of these radionuclides thereby increasing their excretion. DTPA has also been used as a chelator for other metals, such as plutonium.

Preparing Stock Solutions

The following data is based on the product molecular weight 497.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nakamura M, Kido T, Hirai K, Tabo K, Tanabe Y, Kawaguchi N, Kurata A, Kido T, Yamaguchi O, Mochizuki T. What is the mid-wall linear high intensity "lesion" on cardiovascular magnetic resonance late gadolinium enhancement? J Cardiovasc Magn Reson. 2020 Sep 14;22(1):66. doi: 10.1186/s12968-020-00665-5. PMID: 32921308; PMCID: PMC7488664. 2: Bafaraj SM. Significance of nuclear medicine scan in comparison with diethylenetriamine pentaacetic acid and ultrasound imaging in diagnosing renal disorders: An observational study. Medicine (Baltimore). 2020 Sep 4;99(36):e22038. doi: 10.1097/MD.0000000000022038. PMID: 32899061; PMCID: PMC7478558. 3: Zhou W, Hu HJ, Shen B, Shen WQ, Chen H, Wu X, Yan Q, Pang PP. [Application Values of Gadolinium-ethoxybenzyl Diethylenetriaminepentaacetic Acid Enhanced Magnetic Resonance Imaging-based Radiomics in the Quantitative Assessment of Liver Reserve Function of Patients with Liver Cirrhosis]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2020 Aug 30;42(4):459-467. Chinese. doi: 10.3881/j.issn.1000-503X.12620. PMID: 32895097. 4: Wang C, Gao C, Maimaiti W, Li S, Yang Q, Jiang L. The features of technetium-99m-DTPA renal dynamic imaging after severe unilateral ureteral obstruction in adult rabbits. PLoS One. 2020 Aug 19;15(8):e0237443. doi: 10.1371/journal.pone.0237443. PMID: 32813713; PMCID: PMC7437917. 5: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006–. Indium In 111 Pentetate. 2020 Aug 17. PMID: 29999782. 6: Fujita Y, Walton M, Das G, Dohnalkova A, Vanzin G, Anderko A. Impacts of anthropogenic gadolinium on the activity of the ammonia oxidizing bacterium Nitrosomonas europaea. Chemosphere. 2020 Oct;257:127250. doi: 10.1016/j.chemosphere.2020.127250. Epub 2020 Jun 3. PMID: 32600781. 7: Kim SY. Diagnosis of hepatocellular carcinoma: Which MRI contrast agent? Which diagnostic criteria? Clin Mol Hepatol. 2020 Jul;26(3):309-311. doi: 10.3350/cmh.2020.0061. Epub 2020 Jun 15. PMID: 32536046; PMCID: PMC7364363. 8: Zhang J, Winters K, Kiser K, Baboli M, Kim SG. Assessment of tumor treatment response using active contrast encoding (ACE)-MRI: Comparison with conventional DCE-MRI. PLoS One. 2020 Jun 10;15(6):e0234520. doi: 10.1371/journal.pone.0234520. PMID: 32520950; PMCID: PMC7286489. 9: Thị Hue N, Van Hop N, Thai Long H, Hai Phong N, Uyen TH, Quoc Hung L, Nhi Phuong N. Determination of Chromium in Natural Water by Adsorptive Stripping Voltammetry Using In Situ Bismuth Film Electrode. J Environ Public Health. 2020 May 14;2020:1347836. doi: 10.1155/2020/1347836. PMID: 32508934; PMCID: PMC7244981. 10: Xiao B, Wang P, Zhao Y, Liu Y, Ye Z. Nasopharyngeal carcinoma perfusion MRI: Comparison of arterial spin labeling and dynamic contrast-enhanced MRI. Medicine (Baltimore). 2020 May 29;99(22):e20503. doi: 10.1097/MD.0000000000020503. PMID: 32481470. 11: Hui CL, Mautone M. Patterns of enhancement in the hepatobiliary phase of gadoxetic acid-enhanced MRI. Br J Radiol. 2020 Aug;93(1112):20190989. doi: 10.1259/bjr.20190989. Epub 2020 Jun 1. PMID: 32462892; PMCID: PMC7446010. 12: Lin L, Hao X, Li C, Sun C, Wang X, Yin L, Zhang X, Tian J, Yang Y. Impaired glymphatic system in secondary degeneration areas after ischemic stroke in rats. J Stroke Cerebrovasc Dis. 2020 Jul;29(7):104828. doi: 10.1016/j.jstrokecerebrovasdis.2020.104828. Epub 2020 May 11. PMID: 32404284. 13: Hu MJ, Yu YX, Fan YF, Jiang YM, Hu S, Wang XM, Hu CH. [The predictive value of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid enhanced MRI imaging features combined with quantitative parameters for the pathologic grading of hepatocellular carcinoma]. Zhonghua Yi Xue Za Zhi. 2020 May 5;100(17):1299-1304. Chinese. doi: 10.3760/cma.j.cn112137-20191021-02281. PMID: 32375436. 14: Zhao D, Tong BS, Duan ML. [In vivo dynamic changes of inner ear guinea pigs with 9.4 T esla MRI]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Apr 7;55(4):378-383. Chinese. doi: 10.3760/cma.j.cn115330-20190727-00467. PMID: 32306636. 15: Song Y, Han HB, Yang J, Wang AB, He QY, Li YY, Zhao GM, Gao YJ, Wang R, Han YX, Liu AL, Song QW. [Effect of convection enhanced delivery on the microstructure of brain extracellular space in aged rats]. Beijing Da Xue Xue Bao Yi Xue Ban. 2020 Apr 18;52(2):362-367. Chinese. doi: 10.19723/j.issn.1671-167X.2020.02.026. PMID: 32306023; PMCID: PMC7433439. 16: Liu S, Lin X, Shi X, Fang L, Huo L, Shang F, Knuuti J, Han C, Wu X, Guo R, Ding H, Zhang R, Duan H, Ding J, Xing H, Zhao X. Myocardial tissue and metabolism characterization in men with alcohol consumption by cardiovascular magnetic resonance and 11C-acetate PET/CT. J Cardiovasc Magn Reson. 2020 Apr 16;22(1):23. doi: 10.1186/s12968-020-00614-2. PMID: 32299425; PMCID: PMC7161264. 17: Shi W, Liang X, Wu N, Zhang H, Yuan X, Tan Y. Assessment of Split Renal Function Using a Combination of Contrast-Enhanced CT and Serum Creatinine Values for Glomerular Filtration Rate Estimation. AJR Am J Roentgenol. 2020 Jul;215(1):142-147. doi: 10.2214/AJR.19.22125. Epub 2020 Apr 7. PMID: 32255686. 18: Xiao L, Li MH, Dai J, Motelica-Heino M, Chen XF, Wu JL, Zhao L, Liu K, Zhang C. Assessment of earthworm activity on Cu, Cd, Pb and Zn bioavailability in contaminated soils using biota to soil accumulation factor and DTPA extraction. Ecotoxicol Environ Saf. 2020 Jun 1;195:110513. doi: 10.1016/j.ecoenv.2020.110513. Epub 2020 Mar 23. PMID: 32213370. 19: Yu Y, Dang J, Liu X, Wang L, Li S, Zhang T, Ding X. Metal-Labeled Aptamers as Novel Nanoprobes for Imaging Mass Cytometry Analysis. Anal Chem. 2020 May 5;92(9):6312-6320. doi: 10.1021/acs.analchem.9b05159. Epub 2020 Apr 1. PMID: 32208602. 20: Kitoh Y, Miyati T, Tamaru N, Fujinaga Y. [Examination of Gd-EOB-DTPA Liver Dynamic Contrast-enhanced MRI Using Radial VIBE with k-space Weighted Image Contrast Method]. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2020;76(3):270-277. Japanese. doi: 10.6009/jjrt.2020_JSRT_76.3.270. PMID: 32201417.

View History

Lepimectin A4

Lepimectin A4

Featured