Tryptoline, also known as 1,2,3,4-Tetrahydro-β-carboline, is a serotonin reuptake inhibitor and metabolite of tryptamine. In vivo, Tryptoline reduces serotonin levels in rat forebrain. It induces serotonin-mediated hyperactivity syndrome (HHS) in rats. Tryptoline also reduces acetic acid-induced writhing in rats.
MedKoo Cat#: 463116
Name: Tryptoline
CAS#: 16502-01-5
Chemical Formula: C11H12N2
Exact Mass: 172.1000
Molecular Weight: 172.23
Elemental Analysis: C, 76.71; H, 7.02; N, 16.27
The following data is based on the product molecular weight 172.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
