MedKoo Cat#: 111503 | Name: Nabumetone Alcohol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nabumetone alcohol is the alcohol form of nabumetone, a non-steroidal anti-inflammatory drug (NSAID) that is rapidly metabolized in the liver to a major active metabolite, 6-methoxy-2-naphthyl acetic acid, which inhibits the cyclooxygenase enzyme and preferentially blocks COX-2 activity (which is indirectly responsible for the production of inflammation and pain during arthritis).

Chemical Structure

Nabumetone Alcohol
Nabumetone Alcohol
CAS#65726-24-1

Theoretical Analysis

MedKoo Cat#: 111503

Name: Nabumetone Alcohol

CAS#: 65726-24-1

Chemical Formula: C15H18O2

Exact Mass:

Molecular Weight: 230.31

Elemental Analysis: C, 78.23; H, 7.88; O, 13.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
65726-24-1 (alcohol) 42924-53-8 (free)
Synonym
Nabumetone impurity C; Nabumetone impurity; Nabumetone OH
IUPAC/Chemical Name
4-(6-methoxynaphthalen-2-yl)butan-2-ol
InChi Key
JNVOSYBERVWSGY-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H18O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-11,16H,3-4H2,1-2H3
SMILES Code
CC(O)CCC1=CC=C2C=C(OC)C=CC2=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 230.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Long X, Kim YG, Pyo YK, Yi R, Zhao X, Park KY. Inhibitory effect of Jangkanghwan (Korean traditional food) on experimental ulcerative colitis in mice. J Food Biochem. 2020 Dec;44(12):e13488. doi: 10.1111/jfbc.13488. Epub 2020 Oct 4. PMID: 33015841.