MedKoo Cat#: 574847 | Name: Pitavastatin methyl ester

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pitavastatin methyl ester is the methyl ester derivative of Pitavastatin -- a competitive inhibitor of HMG-CoA reductase and an anti-lipemic agent.

Chemical Structure

Pitavastatin methyl ester
Pitavastatin methyl ester
CAS#849811-78-5 (methyl ester)

Theoretical Analysis

MedKoo Cat#: 574847

Name: Pitavastatin methyl ester

CAS#: 849811-78-5 (methyl ester)

Chemical Formula: C26H26FNO4

Exact Mass: 435.1846

Molecular Weight: 435.49

Elemental Analysis: C, 71.71; H, 6.02; F, 4.36; N, 3.22; O, 14.69

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Pitavastatin methyl ester; DOLM
IUPAC/Chemical Name
(3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Methyl Ester
InChi Key
RJYASJYIIVRJNV-OKLSWEBGSA-N
InChi Code
InChI=1S/C26H26FNO4/c1-32-24(31)15-20(30)14-19(29)12-13-22-25(16-8-10-18(27)11-9-16)21-4-2-3-5-23(21)28-26(22)17-6-7-17/h2-5,8-13,17,19-20,29-30H,6-7,14-15H2,1H3/b13-12+/t19-,20-/m1/s1
SMILES Code
O=C(OC)C[C@H](O)C[C@H](O)/C=C/C1=C(C2=CC=C(F)C=C2)C3=CC=CC=C3N=C1C4CC4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 435.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Hoy SM. Pitavastatin: A Review in Hypercholesterolemia. Am J Cardiovasc Drugs. 2017 Apr;17(2):157-168. doi: 10.1007/s40256-017-0213-8. PMID: 28130659. 2. Pirillo A, Catapano AL. Pitavastatin and HDL: Effects on plasma levels and function(s). Atheroscler Suppl. 2017 Jul;27:e1-e9. doi: 10.1016/j.atherosclerosissup.2017.05.001. Epub 2017 May 19. PMID: 28716185.