MedKoo Cat#: 574708 | Name: GBR-13069 dihydrochloride
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GBR-13069 dihydrochloride is a dopamine reuptake inhibitor.

Chemical Structure

GBR-13069 dihydrochloride
GBR-13069 dihydrochloride
CAS#67469-45-8 (2HCl)

Theoretical Analysis

MedKoo Cat#: 574708

Name: GBR-13069 dihydrochloride

CAS#: 67469-45-8 (2HCl)

Chemical Formula: C28H32Cl2F2N2O

Exact Mass: 0.0000

Molecular Weight: 521.47

Elemental Analysis: C, 64.49; H, 6.19; Cl, 13.60; F, 7.29; N, 5.37; O, 3.07

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
50mg USD 1,050.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Synonym
GBR-13069 dihydrochloride; GBR-13069 2HCl; GBR13069; GBR 13069; GBR-12879 dihydrochloride; GBR12879; GBR 12879;
IUPAC/Chemical Name
1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenyl-2-propen-1-yl)piperazine dihydrochloride
InChi Key
ZBSZWEYIIGLGSX-RDRKJGRWSA-N
InChi Code
InChI=1S/C28H30F2N2O.2ClH/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23;;/h1-15,28H,16-22H2;2*1H/b7-4+;;
SMILES Code
FC1=CC=C(C(C2=CC=C(F)C=C2)OCCN3CCN(C/C=C/C4=CC=CC=C4)CC3)C=C1.[H]Cl.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
GBR 13069 dihydrochloride is a potent inhibitor of dopamine uptake (IC50 = 40 nM).
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 521.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1. Heikkila RE, Manzino L. Behavioral properties of GBR 12909, GBR 13069 and GBR 13098: specific inhibitors of dopamine uptake. Eur J Pharmacol. 1984;103(3-4):241-248. doi:10.1016/0014-2999(84)90483-7