sAJM589 suppressed cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage independent growth of Raji cells. Disruption of the Myc-Max interaction by sAJM589 reduced Myc protein levels, possibly by promoting ubiquitination and degradation of Myc. sAJM589 may be a basis for the development of potential inhibitors of Myc-dependent cell growth.
MedKoo Cat#: 565557
Name: sAJM589
CAS#: 2089-82-9
Chemical Formula: C16H10N2O
Exact Mass: 246.0793
Molecular Weight: 246.27
Elemental Analysis: C, 78.03; H, 4.09; N, 11.38; O, 6.50
The following data is based on the product molecular weight 246.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
