NCATS-SM4487 is a galactokinase (GALK1) inhibitor. NCATS-SM4487 was able to reduce gal-1P/protein levels in dose dependence and to ∼50% of control at 3μM.
MedKoo Cat#: 465488
Name: NCATS-SM4487
CAS#: unknown
Chemical Formula: C25H24ClFN8O2
Exact Mass: 522.1695
Molecular Weight: 522.97
Elemental Analysis: C, 57.42; H, 4.63; Cl, 6.78; F, 3.63; N, 21.43; O, 6.12
The following data is based on the product molecular weight 522.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
