DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 potently inhibits PU.1 binding and strongly inhibits the PU.1/DNA complex in vitro. DB1976 has apoptosis-inducing effect.
MedKoo Cat#: 462538
Name: DB1976 hydrochloride
CAS#: 2369663-93-2 (HCl)
Chemical Formula: C20H18Cl2N8Se
Exact Mass: 520.0197
Molecular Weight: 520.28
Elemental Analysis: C, 46.17; H, 3.49; Cl, 13.63; N, 21.54; Se, 15.18
The following data is based on the product molecular weight 520.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
