MedKoo Cat#: 574586 | Name: (±)-N-3-Benzylnirvanol
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol. (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol are inhibitors of the cytochrome P450 (CYP) isoform CYP2C19. (±)-N-3-Benzylnirvanol lowers plasma levels of cholesterol in mice.

Chemical Structure

(±)-N-3-Benzylnirvanol
(±)-N-3-Benzylnirvanol
CAS#93879-40-4

Theoretical Analysis

MedKoo Cat#: 574586

Name: (±)-N-3-Benzylnirvanol

CAS#: 93879-40-4

Chemical Formula: C18H18N2O2

Exact Mass: 294.1368

Molecular Weight: 294.35

Elemental Analysis: C, 73.45; H, 6.16; N, 9.52; O, 10.87

Price and Availability

Size Price Availability Quantity
5mg USD 255.00 2 Weeks
10mg USD 430.00 2 Weeks
25mg USD 755.00 2 Weeks
50mg USD 1,115.00 2 Weeks
100mg USD 1,875.00 2 Weeks
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Synonym
(±)-N-3-Benzylnirvanol
IUPAC/Chemical Name
5-ethyl-5-phenyl-3-(phenylmethyl)-2,4-imidazolidinedione
InChi Key
ZMZDHUHMXXALFX-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H18N2O2/c1-2-18(15-11-7-4-8-12-15)16(21)20(17(22)19-18)13-14-9-5-3-6-10-14/h3-12H,2,13H2,1H3,(H,19,22)
SMILES Code
O=C1N(CC2=CC=CC=C2)C(C(C3=CC=CC=C3)(CC)N1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 294.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Suzuki, H., Kneller, M.B., Haining, R.L., et al. (+)-N-3-Benzyl-nirvanol and (−)-N-3-benzyl-phenobarbital: New potent and selective in vitro inhibitors of CYP2C19. Drug Metab. Dispos. 30(3), 235-239 (2002). 2. Maguire, J.H., Murthy, A.R., and Hall, I.H. Hypolipidemic activity of antiepileptic 5-phenylhydantoins in mice. Eur. J. Pharmacol. 117(1), 135-138 (1985).