Yakkasterone, an oxysterol derived from cholesterol, is formed during the exposure of lung epithelial cells to ozone. It functions as a ligand for liver X receptors (LXRs) and farnesoid X receptors (FXRs), influencing gene expression related to lipid metabolism and inflammation. By binding to these receptors, yakkasterone modulates the expression of genes involved in cholesterol synthesis and uptake, as well as inflammatory pathways.
MedKoo Cat#: 341099
Name: Yakkasterone
CAS#: 13027-33-3
Chemical Formula: C27H46O3
Exact Mass: 418.3447
Molecular Weight: 418.66
Elemental Analysis: C, 77.46; H, 11.08; O, 11.46
The following data is based on the product molecular weight 418.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
