Gendenafil is a phosphodiesterase type 5 (PDE5) inhibitor structurally related to sildenafil, used primarily in the treatment of erectile dysfunction. It enhances nitric oxide–mediated vasodilation by inhibiting the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum. Though less widely known or marketed than other PDE5 inhibitors, gendenafil demonstrates similar pharmacodynamic properties and is under investigation or use in certain regions.
MedKoo Cat#: 574526
Name: Gendenafil
CAS#: 147676-66-2
Chemical Formula: C19H22N4O3
Exact Mass: 354.1692
Molecular Weight: 354.41
Elemental Analysis: C, 64.39; H, 6.26; N, 15.81; O, 13.54
The following data is based on the product molecular weight 354.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
