MedKoo Cat#: 558978 | Name: Sulfo-Cyanine5 bis-NHS ester

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sulfo-Cyanine5 bis-NHS ester is a water soluble bifunctional dye possessing two NHS ester functions. It is an analog of Cy5® bis-NHS ester. The dye is useful for the cross-conjugation of amines, and for other advanced labeling applications.

Chemical Structure

Sulfo-Cyanine5 bis-NHS ester
Sulfo-Cyanine5 bis-NHS ester
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 558978

Name: Sulfo-Cyanine5 bis-NHS ester

CAS#: N/A

Chemical Formula: C45H51KN4O14S2

Exact Mass: 974.2480

Molecular Weight: 975.14

Elemental Analysis: C, 55.43; H, 5.27; K, 4.01; N, 5.75; O, 22.97; S, 6.58

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Synonym
Sulfo-Cy5 bis-NHS ester
IUPAC/Chemical Name
potassium 1-(6-((2,5-dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)-2-((1E,3E)-5-((E)-1-(6-((2,5-dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)-3,3-dimethyl-5-sulfonatoindolin-2-ylidene)penta-1,3-dien-1-yl)-3,3-dimethyl-3H-indol-1-ium-5-sulfonate
InChi Key
OYBBXRFVUWPWJZ-UHFFFAOYSA-M
InChi Code
InChI=1S/C45H52N4O14S2.K/c1-44(2)32-28-30(64(56,57)58)18-20-34(32)46(26-12-6-10-16-42(54)62-48-38(50)22-23-39(48)51)36(44)14-8-5-9-15-37-45(3,4)33-29-31(65(59,60)61)19-21-35(33)47(37)27-13-7-11-17-43(55)63-49-40(52)24-25-41(49)53;/h5,8-9,14-15,18-21,28-29H,6-7,10-13,16-17,22-27H2,1-4H3,(H-,56,57,58,59,60,61);/q;+1/p-1
SMILES Code
CC(C1=CC(S(=O)(O[K])=O)=CC=C1N/2CCCCCC(ON3C(CCC3=O)=O)=O)(C)C2=C/C=C/C=C/C4=[N+](CCCCCC(ON(C(CC5)=O)C5=O)=O)C6=CC=C(S(=O)([O-])=O)C=C6C4(C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 975.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Pettersson, J.R.; Lanni, F.; Rule, G.S. Dual lifetimes for complexes between Glutathione-S-transferase (hGSTA1-1) and product-like ligands detected by single-molecule fluorescence imaging. Biochemistry, 2017, 56(31), 4073–4083. doi: 10.1021/acs.biochem.7b00030