BPK-29 is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein (such RBM45 and SNW1) interactions by covalently modifying C274. BPK-29 impairs the anchorage-independent growth of KEAP1-mutant cancer cells.
MedKoo Cat#: 462423
Name: BPK-29
CAS#: 2143467-62-1 (free base)
Chemical Formula: C26H32ClN3O3
Exact Mass: 469.2132
Molecular Weight: 470.01
Elemental Analysis: C, 66.44; H, 6.86; Cl, 7.54; N, 8.94; O, 10.21
The following data is based on the product molecular weight 470.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
