ACHP is an IκB kinase inhibitor that inhibits DNA binding activity of NF-κB, blocks NF-κB pathway in multiple myeloma cell lines, and induces cell growth arrest and apoptosis. It also inhibits STAT3 signaling in NSCLC in vitro.
MedKoo Cat#: 574495
Name: ACHP free base
CAS#: 406208-42-2 (free base)
Chemical Formula: C21H24N4O2
Exact Mass: 364.1899
Molecular Weight: 364.45
Elemental Analysis: C, 69.21; H, 6.64; N, 15.37; O, 8.78
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 0.0 | 20.00 |
The following data is based on the product molecular weight 364.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
