Cafenstrole | CAS#125306-83-4

MedKoo Cat#: 534972 | Name: Cafenstrole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cafenstrole is a bioactive chemical.

Chemical Structure

Cafenstrole

CAS#125306-83-4

Theoretical Analysis

MedKoo Cat#: 534972

Name: Cafenstrole

CAS#: 125306-83-4

Chemical Formula: C16H22N4O3S

Exact Mass: 350.1413

Molecular Weight: 350.44

Elemental Analysis: C, 54.84; H, 6.33; N, 15.99; O, 13.70; S, 9.15

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Cafenstrole

IUPAC/Chemical Name

1H-1,2,4-Triazole-1-carboxamide, N,N-diethyl-3-mesitylsulfonyl-

InChi Key

HFEJHAAIJZXXRE-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H22N4O3S/c1-6-19(7-2)16(21)20-10-17-15(18-20)24(22,23)14-12(4)8-11(3)9-13(14)5/h8-10H,6-7H2,1-5H3

SMILES Code

O=C(N1N=C(S(=O)(C2=C(C)C=C(C)C=C2C)=O)N=C1)N(CC)CC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 350.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kang G, Kim J, Park H, Kim TH. Crystal structure of cafenstrole. Acta Crystallogr E Crystallogr Commun. 2015 Jul 29;71(Pt 8):o614. doi: 10.1107/S2056989015013869. PMID: 26396825; PMCID: PMC4571425. 2: Abd El-Aty AM, Lee GW, Mamun MI, Choi JH, Cho SK, Shin HC, Shim JH. Development and validation of a method for the analysis of cafenstrole and its metabolite in brown rice grains and rice straw using high-performance liquid chromatography. Biomed Chromatogr. 2008 Mar;22(3):306-15. doi: 10.1002/bmc.934. PMID: 18059057. 3: Jaroensanti-Tanaka N, Miyazaki S, Hosoi A, Tanaka K, Ito S, Iuchi S, Nakano T, Kobayashi M, Nakajima M, Asami T. The chemical NJ15 affects hypocotyl elongation and shoot gravitropism via cutin polymerization. Biosci Biotechnol Biochem. 2018 Oct;82(10):1770-1779. doi: 10.1080/09168451.2018.1484278. Epub 2018 Jun 18. PMID: 29912637. 4: Takahashi H, Ohki A, Kanzaki M, Tanaka A, Sato Y, Matthes B, Böger P, Wakabayashi K. Very-long-chain fatty acid biosynthesis is inhibited by cafenstrole, N,N-diethyl-3-mesitylsulfonyl-1H-1,2,4-triazole-1-carboxamide and its analogs. Z Naturforsch C J Biosci. 2001 Sep-Oct;56(9-10):781-6. doi: 10.1515/znc-2001-9-1016. PMID: 11724382. 5: Park H, Kwon E, Yoon I, Kim J. Crystal structure of catena-poly[[(N ,N-diethyl-3-mesitylsulfonyl-1H-1,2,4-triazole-1-carboxamide-κ N1)silver(I)]-μ-nitrato-κ3O,O':O]. Acta Crystallogr E Crystallogr Commun. 2016 Oct 21;72(Pt 11):1610-1613. doi: 10.1107/S2056989016016662. PMID: 27840720; PMCID: PMC5095845. 6: Jung SC, Kim HG, Kuk YI, Ahn HG, Senseman SA, Lee DJ. Bioavailability of the Nano-Unit 14C-Agrochemicals Under Various Water Potential. J Nanosci Nanotechnol. 2015 Aug;15(8):6206-9. doi: 10.1166/jnn.2015.10447. PMID: 26369226. 7: Yang X, Guschina IA, Hurst S, Wood S, Langford M, Hawkes T, Harwood JL. The action of herbicides on fatty acid biosynthesis and elongation in barley and cucumber. Pest Manag Sci. 2010 Jul;66(7):794-800. doi: 10.1002/ps.1944. PMID: 20533380. 8: Ma Y, Liu R, Gong X, Li Z, Huang Q, Wang H, Song G. Synthesis and herbicidal activity of N,N-diethyl-3-(arylselenonyl)-1H-1,2,4-triazole-1-carboxamide. J Agric Food Chem. 2006 Oct 4;54(20):7724-8. doi: 10.1021/jf0609328. PMID: 17002445. 9: Jung SC, Kuk YI, Senseman SA, Ahn HG, Seong CN, Lee DJ. Bioactivity of Several Herbicides on the Nanogram Level Under Different Soil Moisture Conditions. J Nanosci Nanotechnol. 2015 Jan;15(1):676-9. doi: 10.1166/jnn.2015.8370. PMID: 26328425. 10: Tsuda T, Nakamura T, Inoue A, Tanaka K. Pesticides in water, fish and shellfish from littoral area of Lake Biwa. Bull Environ Contam Toxicol. 2009 Jun;82(6):716-21. doi: 10.1007/s00128-009-9681-0. Epub 2009 Mar 10. PMID: 19277442. 11: Eckermann C, Matthes B, Nimtz M, Reiser V, Lederer B, Böger P, Schröder J. Covalent binding of chloroacetamide herbicides to the active site cysteine of plant type III polyketide synthases. Phytochemistry. 2003 Nov;64(6):1045-54. doi: 10.1016/s0031-9422(03)00516-8. PMID: 14568070. 12: Nobusawa T, Okushima Y, Nagata N, Kojima M, Sakakibara H, Umeda M. Synthesis of very-long-chain fatty acids in the epidermis controls plant organ growth by restricting cell proliferation. PLoS Biol. 2013;11(4):e1001531. doi: 10.1371/journal.pbio.1001531. Epub 2013 Apr 9. PMID: 23585732; PMCID: PMC3621670. 13: Nobusawa T, Umeda M. Very-long-chain fatty acids have an essential role in plastid division by controlling Z-ring formation in Arabidopsis thaliana. Genes Cells. 2012 Aug;17(8):709-19. doi: 10.1111/j.1365-2443.2012.01619.x. Epub 2012 Jun 27. PMID: 22734690.