MedKoo Cat#: 462260 | Name: TC HSD 21
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor. It shows excellent selectivity over 17β-HSD isoenzymes and nuclear receptors.

Chemical Structure

TC HSD 21
TC HSD 21
CAS#330203-01-5

Theoretical Analysis

MedKoo Cat#: 462260

Name: TC HSD 21

CAS#: 330203-01-5

Chemical Formula: C17H12BrNO3S2

Exact Mass: 420.9442

Molecular Weight: 422.31

Elemental Analysis: C, 48.35; H, 2.86; Br, 18.92; N, 3.32; O, 11.37; S, 15.18

Price and Availability

Size Price Availability Quantity
1mg USD 320.00 2 Weeks
5mg USD 590.00 2 Weeks
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Related CAS #
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Synonym
TC HSD 21; TCHSD21; TCHSD021; TC-HSD21
IUPAC/Chemical Name
(Z)-5-(3-bromo-4-hydroxybenzylidene)-3-(4-methoxyphenyl)-2-thioxothiazolidin-4-one
InChi Key
HEFKAUYVLSGPGC-DHDCSXOGSA-N
InChi Code
InChI=1S/C17H12BrNO3S2/c1-22-12-5-3-11(4-6-12)19-16(21)15(24-17(19)23)9-10-2-7-14(20)13(18)8-10/h2-9,20H,1H3/b15-9-
SMILES Code
OC1=CC=C(/C=C2SC(N(C3=CC=C(OC)C=C3)C\2=O)=S)C=C1Br
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 422.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Harada K, Kubo H, Tanaka A, Nishioka K. Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors. Bioorg Med Chem Lett. 2012;22(1):504-507. doi:10.1016/j.bmcl.2011.10.095