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MedKoo Cat#: 591172 | Name: NSC 56775
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

NSC 56775, also known as Bis(2-ethylhexyl)hexanedioate is a diester resulting from the formal condensation of the carboxy groups of adipic acid with 2-ethylhexan-1-ol. It is used as a plasticiser in the preparation of various polymers.

Chemical Structure

NSC 56775
NSC 56775
CAS#103-23-1

Theoretical Analysis

MedKoo Cat#: 591172

Name: NSC 56775

CAS#: 103-23-1

Chemical Formula: C22H42O4

Exact Mass: 370.3083

Molecular Weight: 370.57

Elemental Analysis: C, 71.31; H, 11.42; O, 17.27

Price and Availability

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1kg USD 340.00 2 weeks
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Synonym
Bis(2-ethylhexyl)hexanedioate; NSC 56775; NSC-56775; NSC56775
IUPAC/Chemical Name
Bis(2-ethylhexyl) adipate
InChi Key
SAOKZLXYCUGLFA-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H42O4/c1-5-9-13-19(7-3)17-25-21(23)15-11-12-16-22(24)26-18-20(8-4)14-10-6-2/h19-20H,5-18H2,1-4H3
SMILES Code
O=C(OCC(CC)CCCC)CCCCC(OCC(CC)CCCC)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Product Data
Instruction
View handling instruction
Biological target:
NSC 56775, also known as Bis(2-ethylhexyl)hexanedioate is a diester resulting from the formal condensation of the carboxy groups of adipic acid with 2-ethylhexan-1-ol.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 370.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Aneck-Hahn NH, Van Zijl MC, Swart P, Truebody B, Genthe B, Charmier J, Jager C. Estrogenic activity, selected plasticizers and potential health risks associated with bottled water in South Africa. J Water Health. 2018 Apr;16(2):253-262. doi: 10.2166/wh.2018.043. PubMed PMID: 29676761; PubMed Central PMCID: wh_2018_043. 2: Jeon SH, Kim YP, Kho Y, Shin JH, Ji WH, Ahn YG. Development and Validation of Gas Chromatography-Triple Quadrupole Mass Spectrometric Method for Quantitative Determination of Regulated Plasticizers in Medical Infusion Sets. J Anal Methods Chem. 2018 Feb 5;2018:9470254. doi: 10.1155/2018/9470254. eCollection 2018. PubMed PMID: 29629214; PubMed Central PMCID: PMC5832103. 3: Socas-Rodríguez B, González-Sálamo J, Herrera-Herrera AV, Santana-Mayor Á, Hernández-Borges J. Determination of phthalic acid esters in different baby food samples by gas chromatography tandem mass spectrometry. Anal Bioanal Chem. 2018 Mar 9. doi: 10.1007/s00216-018-0977-y. [Epub ahead of print] PubMed PMID: 29523939. 4: Rubio L, Sarabia LA, Ortiz MC. Effect of the cleaning procedure of Tenax on its reuse in the determination of plasticizers after migration by gas chromatography/mass spectrometry. Talanta. 2018 May 15;182:505-522. doi: 10.1016/j.talanta.2018.02.011. Epub 2018 Feb 8. PubMed PMID: 29501186. 5: González-Sálamo J, Socas-Rodríguez B, Hernández-Borges J, Rodríguez-Delgado MÁ. Determination of phthalic acid esters in water samples using core-shell poly(dopamine) magnetic nanoparticles and gas chromatography tandem mass spectrometry. J Chromatogr A. 2017 Dec 29;1530:35-44. doi: 10.1016/j.chroma.2017.11.013. Epub 2017 Nov 8. PubMed PMID: 29146426. 6: Boran H, Terzi S. Stress-Induced Transcriptional Changes and DNA Damage Associated with Bis(2-ethylhexyl) Adipate Exposure in Zebrafish (Danio rerio) Larvae. Bull Environ Contam Toxicol. 2017 Sep;99(3):308-314. doi: 10.1007/s00128-017-2116-4. Epub 2017 May 24. PubMed PMID: 28536799. 7: Alves A, Giovanoulis G, Nilsson U, Erratico C, Lucattini L, Haug LS, Jacobs G, de Wit CA, Leonards PE, Covaci A, Magner J, Voorspoels S. Case Study on Screening Emerging Pollutants in Urine and Nails. Environ Sci Technol. 2017 Apr 4;51(7):4046-4053. doi: 10.1021/acs.est.6b05661. Epub 2017 Mar 22. PubMed PMID: 28293951. 8: Masse M, Genay S, Feutry F, Simon N, Barthélémy C, Sautou V, Décaudin B, Odou P, For The Armed Study Group. How to solve the problem of co-elution between two compounds in liquid chromatography through the first UV derivative spectrum. A trial on alternative plasticizers to di(2-ethylhexyl) phthalate. Talanta. 2017 Jan 1;162:187-192. doi: 10.1016/j.talanta.2016.10.029. Epub 2016 Oct 4. PubMed PMID: 27837816. 9: Oca ML, Rubio L, Sarabia LA, Ortiz MC. Dealing with the ubiquity of phthalates in the laboratory when determining plasticizers by gas chromatography/mass spectrometry and PARAFAC. J Chromatogr A. 2016 Sep 16;1464:124-40. doi: 10.1016/j.chroma.2016.07.074. Epub 2016 Jul 29. PubMed PMID: 27507728. 10: Kranz W, Kitts K, Strange N, Cummins J, Lotspeich E, Goodpaster J. On the smell of Composition C-4. Forensic Sci Int. 2014 Mar;236:157-63. doi: 10.1016/j.forsciint.2013.12.012. Epub 2013 Dec 24. PubMed PMID: 24529788. 11: Jakubowska N, Beldì G, Peychès Bach A, Simoneau C. Optimisation of an analytical method and results from the inter-laboratory comparison of the migration of regulated substances from food packaging into the new mandatory European Union simulant for dry foodstuffs. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2014;31(3):546-55. doi: 10.1080/19440049.2013.874046. Epub 2014 Feb 21. PubMed PMID: 24409838. 12: Aragón M, Borrull F, Marcé RM. Thermal desorption-gas chromatography-mass spectrometry method to determine phthalate and organophosphate esters from air samples. J Chromatogr A. 2013 Aug 16;1303:76-82. doi: 10.1016/j.chroma.2013.06.025. Epub 2013 Jun 19. PubMed PMID: 23859797. 13: Ontiveros JF, Pierlot C, Catté M, Molinier V, Pizzino A, Salager JL, Aubry JM. Classification of ester oils according to their Equivalent Alkane Carbon Number (EACN) and asymmetry of fish diagrams of C10E4/ester oil/water systems. J Colloid Interface Sci. 2013 Aug 1;403:67-76. doi: 10.1016/j.jcis.2013.03.071. Epub 2013 Apr 22. PubMed PMID: 23673005. 14: Aragón M, Marcé RM, Borrull F. Determination of phthalates and organophosphate esters in particulated material from harbour air samples by pressurised liquid extraction and gas chromatography-mass spectrometry. Talanta. 2012 Nov 15;101:473-8. doi: 10.1016/j.talanta.2012.09.062. Epub 2012 Oct 5. PubMed PMID: 23158351. 15: Hassan AK, Saad B, Ghani SA, Adnan R, Rahim AA, Ahmad N, Mokhtar M, Ameen ST, Al-Araji SM. Ionophore-based potentiometric sensors for the flow-injection determination of promethazine hydrochloride in pharmaceutical formulations and human urine. Sensors (Basel). 2011;11(1):1028-42. doi: 10.3390/s110101028. Epub 2011 Jan 18. PubMed PMID: 22346617; PubMed Central PMCID: PMC3274102. 16: Guart A, Bono-Blay F, Borrell A, Lacorte S. Migration of plasticizers phthalates, bisphenol A and alkylphenols from plastic containers and evaluation of risk. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011 May;28(5):676-85. doi: 10.1080/19440049.2011.555845. PubMed PMID: 21400322. 17: Guo Z, Wang S, Wei D, Wang M, Zhang H, Gai P, Duan J. Development and application of a method for analysis of phthalates in ham sausages by solid-phase extraction and gas chromatography-mass spectrometry. Meat Sci. 2010 Mar;84(3):484-90. doi: 10.1016/j.meatsci.2009.10.002. Epub 2009 Oct 8. PubMed PMID: 20374814. 18: Guo ZY, Gai PP, Duan J, Zhai JX, Zhao SS, Wang S, Wei DY. Simultaneous determination of phthalates and adipates in human serum using gas chromatography-mass spectrometry with solid-phase extraction. Biomed Chromatogr. 2010 Oct;24(10):1094-9. doi: 10.1002/bmc.1410. PubMed PMID: 20352652. 19: Rothenbacher T, Schwack W. Rapid identification of additives in poly(vinyl chloride) lid gaskets by direct analysis in real time ionisation and single-quadrupole mass spectrometry. Rapid Commun Mass Spectrom. 2010 Jan;24(1):21-9. doi: 10.1002/rcm.4350. PubMed PMID: 19957297. 20: Llop A, Borrull F, Pocurull E. Comparison of the removal of phthalates and other organic pollutants from industrial wastewaters in membrane bioreactor and conventional activated sludge treatment plants. Water Sci Technol. 2009;60(9):2425-37. doi: 10.2166/wst.2009.314. PubMed PMID: 19901476.