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MedKoo Cat#: 574469 | Name: Ciprofloxacin Lactate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ciprofloxacin Lactate is an antibiotic that been shown to produce high and sustained serum bactericidal titers against highly susceptible bacteria.

Chemical Structure

Ciprofloxacin Lactate
CAS#97867-33-9 (lactate)

Theoretical Analysis

MedKoo Cat#: 574469

Name: Ciprofloxacin Lactate

CAS#: 97867-33-9 (lactate)

Chemical Formula: C20H24FN3O6

Exact Mass: 421.1649

Molecular Weight: 421.42

Elemental Analysis: C, 57.00; H, 5.74; F, 4.51; N, 9.97; O, 22.78

Price and Availability

Size Price Availability Quantity
1g USD 250.00 2 Weeks
2g USD 400.00 2 Weeks
5g USD 750.00 2 Weeks
10g USD 1,150.00 2 Weeks
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Related CAS #
85721-33-1 (free base) 86393-32-0 (HCl hydrate) 86483-48-9 (xHCl) 93107-08-5 (HCl) 96186-80-0 (lactate) 97867-33-9 (lactate)
Synonym
Ciprofloxacin Lactate; Cipobacter; Ificipro
IUPAC/Chemical Name
1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-Quinolinecarboxylic Acid Mono(2-hydroxypropanoate)
InChi Key
NRBJWZSFNGZBFQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H18FN3O3.C3H6O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;1-2(4)3(5)6/h7-10,19H,1-6H2,(H,23,24);2,4H,1H3,(H,5,6)
SMILES Code
O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CCNCC4)=C3)C1=O)O.CC(O)C(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 421.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhang GF, Liu X, Zhang S, Pan B, Liu ML. Ciprofloxacin derivatives and their antibacterial activities. Eur J Med Chem. 2018 Feb 25;146:599-612. doi: 10.1016/j.ejmech.2018.01.078. Epub 2018 Feb 4. PMID: 29407984. 2: Terp DK, Rybak MJ. Ciprofloxacin. Drug Intell Clin Pharm. 1987 Jul- Aug;21(7-8):568-74. doi: 10.1177/1060028087021007-801. PMID: 3301247. 3: Campoli-Richards DM, Monk JP, Price A, Benfield P, Todd PA, Ward A. Ciprofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1988 Apr;35(4):373-447. doi: 10.2165/00003495-198835040-00003. PMID: 3292209. 4: Shariati A, Arshadi M, Khosrojerdi MA, Abedinzadeh M, Ganjalishahi M, Maleki A, Heidary M, Khoshnood S. The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic. Front Public Health. 2022 Dec 21;10:1025633. doi: 10.3389/fpubh.2022.1025633. PMID: 36620240; PMCID: PMC9815622. 5: Badawy S, Yang Y, Liu Y, Marawan MA, Ares I, Martinez MA, Martínez-Larrañaga MR, Wang X, Anadón A, Martínez M. Toxicity induced by ciprofloxacin and enrofloxacin: oxidative stress and metabolism. Crit Rev Toxicol. 2021 Oct;51(9):754-787. doi: 10.1080/10408444.2021.2024496. PMID: 35274591. 6: Kulshrestha SP, Barar FS, Miglani N. Ciprofloxacin. Indian Pediatr. 1990 Aug;27(8):849-53. PMID: 2152246. 7: Tossing G. 99mTc-ciprofloxacin DRAXIMAGE. IDrugs. 2004 Apr;7(4):374-9. PMID: 15057643. 8: Smyth EG, Pallet AP. Ciprofloxacin. Br J Hosp Med. 1989 Jan;41(1):62, 66-7. PMID: 2924060. 9: Sterman BM. Ciprofloxacin. Laryngoscope. 1989 Nov;99(11):1211-2. doi: 10.1288/00005537-198911000-00022. PMID: 2811565. 10: Ciprofloxacin. Med Lett Drugs Ther. 1988 Jan 29;30(758):11-3. PMID: 3277024. 11: Hoey LL, Lake KD. Does ciprofloxacin interact with cyclosporine? Ann Pharmacother. 1994 Jan;28(1):93-6. doi: 10.1177/106002809402800117. PMID: 8123970. 12: Nix DE, DeVito JM. Ciprofloxacin and norfloxacin, two fluoroquinolone antimicrobials. Clin Pharm. 1987 Feb;6(2):105-17. PMID: 3311572. 13: Wiseman LR, Balfour JA. Ciprofloxacin. A review of its pharmacological profile and therapeutic use in the elderly. Drugs Aging. 1994 Feb;4(2):145-73. doi: 10.2165/00002512-199404020-00007. PMID: 8186542. 14: Hessen MT, Levison ME. Ciprofloxacin for the treatment of osteomyelitis: a review. J Foot Surg. 1989 Mar-Apr;28(2):100-5. PMID: 2661635. 15: Kaguelidou F, Turner MA, Choonara I, Jacqz-Aigrain E. Ciprofloxacin use in neonates: a systematic review of the literature. Pediatr Infect Dis J. 2011 Feb;30(2):e29-37. doi: 10.1097/INF.0b013e3181fe353d. PMID: 21048525. 16: Davis R, Markham A, Balfour JA. Ciprofloxacin. An updated review of its pharmacology, therapeutic efficacy and tolerability. Drugs. 1996 Jun;51(6):1019-74. doi: 10.2165/00003495-199651060-00010. PMID: 8736621. 17: Fogazzi GB, Garigali G, Brambilla C, Daudon M. Ciprofloxacin crystalluria. Nephrol Dial Transplant. 2006 Oct;21(10):2982-3. doi: 10.1093/ndt/gfl320. Epub 2006 Jul 12. PMID: 16837513. 18: Santucci R, Bouayad-Agha K, Maloisel F, Couturier F. Thrombocytopénie induite par la ciprofloxacine [Ciprofloxacin-induced thrombopenia]. Med Mal Infect. 2012 Apr;42(4):175-6. French. doi: 10.1016/j.medmal.2012.02.008. Epub 2012 Apr 3. PMID: 22475418. 19: Balfour JA, Faulds D. Oral ciprofloxacin: a pharmacoeconomic evaluation of its use in the treatment of serious infections. Pharmacoeconomics. 1993 May;3(5):398-421. doi: 10.2165/00019053-199303050-00007. PMID: 10146890. 20: Vance-Bryan K, Guay DR, Rotschafer JC. Clinical pharmacokinetics of ciprofloxacin. Clin Pharmacokinet. 1990 Dec;19(6):434-61. doi: 10.2165/00003088-199019060-00003. PMID: 2292168.

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