MedKoo Cat#: 462232 | Name: FGI-106 HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

FGI-106 is a broad-spectrum antiviral drug developed as a potential treatment for enveloped RNA viruses, in particular viral hemorrhagic fevers from the bunyavirus, flavivirus and filovirus families. It acts as an inhibitor which blocks viral entry into host cells. In animal tests FGI-106 shows both prophylactic and curative action against a range of deadly viruses for which few existing treatments are available, including the bunyaviruses hantavirus, Rift Valley fever virus and Crimean-Congo hemorrhagic fever virus, the flavivirus dengue virus, and the filoviruses Ebola virus and Marburg virus.

Chemical Structure

FGI-106 HCl
FGI-106 HCl
CAS#1149348-10-6 (4HCl)

Theoretical Analysis

MedKoo Cat#: 462232

Name: FGI-106 HCl

CAS#: 1149348-10-6 (4HCl)

Chemical Formula: C28H42Cl4N6

Exact Mass: 458.3158

Molecular Weight: 604.49

Elemental Analysis: C, 55.64; H, 7.00; Cl, 23.46; N, 13.90

Price and Availability

Size Price Availability Quantity
25mg USD 950.00 2 Weeks
50mg USD 1,650.00 2 Weeks
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Related CAS #
1149348-10-6 (4HCl) 501081-38-5 (free base)
Synonym
FGI-106; FGI106; FGI 106; FGI-106 HCl; FGI-106 hydrochloride; FGI-106 tetrahydrochloride;
IUPAC/Chemical Name
N1,N7-bis[3-(dimethylamino)propyl]-3,9-dimethylquinolino[8,7-h]quinoline-1,7-diamine tetrahydrochloride
InChi Key
YUQCVPFHAFZFPV-UHFFFAOYSA-N
InChi Code
InChI=1S/C28H38N6.4ClH/c1-19-17-25(29-13-7-15-33(3)4)23-11-10-22-21(27(23)31-19)9-12-24-26(18-20(2)32-28(22)24)30-14-8-16-34(5)6;;;;/h9-12,17-18H,7-8,13-16H2,1-6H3,(H,29,31)(H,30,32);4*1H
SMILES Code
CC1=CC(NCCCN(C)C)=C2C=CC3=C4N=C(C)C=C(NCCCN(C)C)C4=CC=C3C2=N1.[H]Cl.[H]Cl.[H]Cl.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 604.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Aman MJ, Kinch MS, Warfield K, et al. Development of a broad-spectrum antiviral with activity against Ebola virus. Antiviral Res. 2009;83(3):245-251. doi:10.1016/j.antiviral.2009.06.001