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MedKoo Cat#: 599289 | Name: LSZ

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LSZ is an analog of LSD.

Chemical Structure

LSZ
LSZ
CAS#470666-31-0

Theoretical Analysis

MedKoo Cat#: 599289

Name: LSZ

CAS#: 470666-31-0

Chemical Formula: C21H25N3O

Exact Mass: 335.1998

Molecular Weight: 335.45

Elemental Analysis: C, 75.19; H, 7.51; N, 12.53; O, 4.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
LSZ;
IUPAC/Chemical Name
((2S,4S)-2,4-dimethylazetidin-1-yl)((6aR,9R)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinolin-9-yl)methanone
InChi Key
DUKNIHFTDAXJON-CTQRGLTFSA-N
InChi Code
1S/C21H25N3O/c1-12-7-13(2)24(12)21(25)15-8-17-16-5-4-6-18-20(16)14(10-22-18)9-19(17)23(3)11-15/h4-6,8,10,12-13,15,19,22H,7,9,11H2,1-3H3/t12-,13-,15+,19+/m0/s1
SMILES Code
C[C@H]1C[C@H](C)N1C([C@H]2CN(C)[C@@H]3Cc4c5c(C3=C2)cccc5[nH]c4)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 335.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Interaction between lysozyme and humic acid in layer-by-layer assemblies: effects of pH and ionic strength. J Colloid Interface Sci. 2014 Sep 15;430:40-6. doi: 10.1016/j.jcis.2014.05.029. Epub 2014 Jun 2. PubMed PMID: 24998052. 5: Ei Ei H, Nakama Y, Tanaka H, Imanaka H, Ishida N, Imamura K. Adsorption of lysozyme on base metal surfaces in the presence of an external electric potential. Colloids Surf B Biointerfaces. 2016 Nov 1;147:9-16. doi: 10.1016/j.colsurfb.2016.07.042. Epub 2016 Jul 25. PubMed PMID: 27478958. 6: Jachimska B, Kozłowska A, Pajor-Świerzy A. Protonation of lysozymes and its consequences for the adsorption onto a mica surface. Langmuir. 2012 Aug 7;28(31):11502-10. doi: 10.1021/la301558u. Epub 2012 Jul 24. PubMed PMID: 22783827. 7: Kang YQ, Zhao C, Chen AZ, Wang SB, Liu YG, Wu WG, Su XQ. Study of Lysozyme-Loaded Poly-L-Lactide (PLLA) Porous Microparticles in a Compressed CO₂ Antisolvent Process. Materials (Basel). 2013 Aug 19;6(8):3571-3583. doi: 10.3390/ma6083571. PubMed PMID: 28811453; PubMed Central PMCID: PMC5521323. 8: Horn DW, Davis VA. Concentration of lysozyme/single-walled carbon nanotube dispersions. Colloids Surf B Biointerfaces. 2016 Mar 1;139:237-43. doi: 10.1016/j.colsurfb.2015.11.040. Epub 2015 Dec 2. PubMed PMID: 26722820. 9: Li CY, Zhang J, Chu JH, Xu MJ, Ju WZ, Liu F, Jian-Dong Z. A correlative study of polymorphisms of CYP2C19 and MDR1 C3435T with the pharmacokinetic profiles of lansoprazole and its main metabolites following single oral administration in healthy adult Chinese subjects. Eur J Drug Metab Pharmacokinet. 2014 Jun;39(2):121-8. PubMed PMID: 24022708. 10: Lukina E, Laka A, Kollerov M, Sampiev M, Mason P, Wagstaff P, Noordeen H, Yoon WW, Blunn G. Metal concentrations in the blood and tissues after implantation of titanium growth guidance sliding instrumentation. Spine J. 2016 Mar;16(3):380-8. doi: 10.1016/j.spinee.2015.11.040. Epub 2015 Dec 2. PubMed PMID: 26656164. 11: Hong XP, Xu D, Zhuo Y, Liu HQ, Lu LQ. Identification and pathogenicity of Vibrio parahaemolyticus isolates and immune responses of Penaeus (Litopenaeus) vannamei (Boone). J Fish Dis. 2016 Sep;39(9):1085-97. doi: 10.1111/jfd.12441. Epub 2016 Jan 13. PubMed PMID: 26763100. 12: Wang X, Herting G, Wallinder IO, Blomberg E. Adsorption of lysozyme on silver and its influence on silver release. Langmuir. 2014 Nov 25;30(46):13877-89. doi: 10.1021/la503170x. Epub 2014 Nov 14. PubMed PMID: 25363360. 13: Kong X, Wang S, Jiang H, Nie G, Li X. Responses of acid/alkaline phosphatase, lysozyme, and catalase activities and lipid peroxidation to mercury exposure during the embryonic development of goldfish Carassius auratus. Aquat Toxicol. 2012 Sep 15;120-121:119-25. doi: 10.1016/j.aquatox.2012.05.005. Epub 2012 May 22. PubMed PMID: 22683699. 14: Brasca M, Morandi S, Silvetti T, Rosi V, Cattaneo S, Pellegrino L. Different analytical approaches in assessing antibacterial activity and the purity of commercial lysozyme preparations for dairy application. Molecules. 2013 May 21;18(5):6008-20. doi: 10.3390/molecules18056008. PubMed PMID: 23698052. 15: Kandori K, Oketani M, Wakamura M. Effects of Ti(IV) substitution on protein adsorption behaviors of calcium hydroxyapatite particles. Colloids Surf B Biointerfaces. 2013 Jan 1;101:68-73. doi: 10.1016/j.colsurfb.2012.06.017. Epub 2012 Jul 3. PubMed PMID: 22809592. 16: Nepal D, Minus ML, Kumar S. Lysozyme coated DNA and DNA/SWNT fibers by solution spinning. Macromol Biosci. 2011 Jul 7;11(7):875-81. doi: 10.1002/mabi.201000490. Epub 2011 Apr 5. PubMed PMID: 21472979. 17: Du Y, Yi M, Xiao P, Meng L, Li X, Sun G, Liu Y. The impact of Aeromonas salmonicida infection on innate immune parameters of Atlantic salmon (Salmo salar L). Fish Shellfish Immunol. 2015 May;44(1):307-15. doi: 10.1016/j.fsi.2015.02.029. Epub 2015 Feb 25. PubMed PMID: 25725402. 18: Meder F, Kaur S, Treccani L, Rezwan K. Controlling mixed-protein adsorption layers on colloidal alumina particles by tailoring carboxyl and hydroxyl surface group densities. Langmuir. 2013 Oct 8;29(40):12502-10. doi: 10.1021/la402093j. Epub 2013 Jul 31. PubMed PMID: 23875793. 19: Tan WF, Koopal LK, Norde W. Interaction between humic acid and lysozyme, studied by dynamic light scattering and isothermal titration calorimetry. Environ Sci Technol. 2009 Feb 1;43(3):591-6. PubMed PMID: 19244988. 20: Charnvanich D, Vardhanabhuti N, Kulvanich P. Effect of cholesterol on the properties of spray-dried lysozyme-loaded liposomal powders. AAPS PharmSciTech. 2010 Jun;11(2):832-42. doi: 10.1208/s12249-010-9442-8. Epub 2010 May 13. PubMed PMID: 20464536; PubMed Central PMCID: PMC2902320.

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EP-459

EP-459