MedKoo Cat#: 534874 | Name: MZ 472

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MZ 472 is a bioactive chemical.

Chemical Structure

MZ 472
MZ 472
CAS#54978-27-7

Theoretical Analysis

MedKoo Cat#: 534874

Name: MZ 472

CAS#: 54978-27-7

Chemical Formula: C18H25N5O3

Exact Mass: 359.1957

Molecular Weight: 359.43

Elemental Analysis: C, 60.15; H, 7.01; N, 19.49; O, 13.35

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
MZ 472; MZ-472; MZ472
IUPAC/Chemical Name
4H-Pyrido(1,2-a)pyrimidin-4-one, 6,7,8,9-tetrahydro-6-methyl-3-(((2-oxo-3-oxazolidinyl)imino)methyl)-2-(1-piperidinyl)-
InChi Key
BEHZJFKCIRHHBO-XDHOZWIPSA-N
InChi Code
InChI=1S/C18H25N5O3/c1-13-6-5-7-15-20-16(21-8-3-2-4-9-21)14(17(24)23(13)15)12-19-22-10-11-26-18(22)25/h12-13H,2-11H2,1H3/b19-12+
SMILES Code
O=C1C(/C=N/N2C(OCC2)=O)=C(N3CCCCC3)N=C4N1C(C)CCC4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 359.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Muhle R, Trentacoste SV, Rapin I. The genetics of autism. Pediatrics. 2004 May;113(5):e472-86. doi: 10.1542/peds.113.5.e472. PMID: 15121991. 2: Štenglová-Netíková IR, Petruželka L, Šťastný M, Štengl V. Anthracycline antibiotics derivate mitoxantrone-Destructive sorption and photocatalytic degradation. PLoS One. 2018 Mar 13;13(3):e0193116. doi: 10.1371/journal.pone.0193116. PMID: 29534071; PMCID: PMC5849306. 3: van Dongen J, Nivard MG, Baselmans BM, Zilhão NR, Ligthart L; BIOS Consortium, Heijmans BT, Bartels M, Boomsma DI. Epigenome-Wide Association Study of Aggressive Behavior. Twin Res Hum Genet. 2015 Dec;18(6):686-98. doi: 10.1017/thg.2015.74. Epub 2015 Oct 28. PMID: 26508088. 4: Hakim AJ, Cherkas LF, Grahame R, Spector TD, MacGregor AJ. The genetic epidemiology of joint hypermobility: a population study of female twins. Arthritis Rheum. 2004 Aug;50(8):2640-4. doi: 10.1002/art.20376. PMID: 15334479. 5: Liu X, Zhang S, Tsai HJ, Hong X, Wang B, Fang Y, Liu X, Pongracic JA, Wang X. Genetic and environmental contributions to allergen sensitization in a Chinese twin study. Clin Exp Allergy. 2009 Jul;39(7):991-8. doi: 10.1111/j.1365-2222.2009.03228.x. Epub 2009 Mar 17. PMID: 19302247; PMCID: PMC2756049. 6: Scheet P, Ehli EA, Xiao X, van Beijsterveldt CE, Abdellaoui A, Althoff RR, Hottenga JJ, Willemsen G, Nelson KA, Huizenga PE, Hu Y, Amos CI, Bartels M, Groen-Blokhuis MM, de Geus EJ, Hudziak JJ, Davies GE, Boomsma DI. Twins, tissue, and time: an assessment of SNPs and CNVs. Twin Res Hum Genet. 2012 Dec;15(6):737-45. doi: 10.1017/thg.2012.61. Epub 2012 Sep 28. PMID: 23021707; PMCID: PMC5540648. 7: de Souza Barbosa F, Cassol JPE, Batista LADC, Cordeiro EWF, Santos MC, Pohlmann AR, Schapoval EES, Garcia CV, Mendez ASL. Stability of doripenem in reconstituted solution - thermal and oxidative decomposition kinetics and degradation products by LC-MS. Biomed Chromatogr. 2017 Aug;31(8). doi: 10.1002/bmc.3940. Epub 2017 Mar 10. PMID: 28135762. 8: Goparaju SM, Nandula YSM, Bannoth Kothapalli C, Challa BR, Awen BZ. Method development and validation of Guanfacine in rat plasma by liquid chromatography- tandem mass spectrometry: Application to a pharmacokinetic study. J Pharm Anal. 2013 Dec;3(6):472-480. doi: 10.1016/j.jpha.2013.04.006. Epub 2013 Jun 27. PMID: 29403858; PMCID: PMC5760995. 9: Karampela S, Pistos C, Moraitis K, Stoukas V, Papoutsis I, Zorba E, Koupparis M, Spiliopoulou C, Athanaselis S. Development and validation of a LC/MS method for the determination of Δ(9)-tetrahydrocannabinol and 11-carboxy-Δ(9)-tetrahydrocannabinol in the larvae of the blowfly Lucilia sericata: Forensic applications. Sci Justice. 2015 Dec;55(6):472-80. doi: 10.1016/j.scijus.2015.06.003. Epub 2015 Jun 17. PMID: 26654083. 10: Zhou L, Qian J, Liu J, Zhao R, Li B, Wang R. Identification of the sites of 4-hydroxy-2-nonenal and neprilysin adduction using a linear trap quadrapole Velos Pro-Orbitrap Elite mass spectrometer. Eur J Mass Spectrom (Chichester). 2016;22(3):133-9. doi: 10.1255/ejms.1420. PMID: 27553735. 11: Kinsella B, Byrne P, Cantwell H, McCormack M, Furey A, Danaher M. Determination of the new anthelmintic monepantel and its sulfone metabolite in milk and muscle using a UHPLC-MS/MS and QuEChERS method. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Dec 1;879(31):3707-13. doi: 10.1016/j.jchromb.2011.10.011. Epub 2011 Oct 14. PMID: 22041088. 12: Inoue K, Ikemura A, Tsuruta Y, Watanabe K, Tsutsumiuchi K, Hino T, Oka H. Quantification of N-acetyl-seryl-aspartyl-lysyl-proline in hemodialysis patients administered angiotensin-converting enzyme inhibitors by stable isotope dilution liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2011 Mar 25;54(4):765-71. doi: 10.1016/j.jpba.2010.10.009. Epub 2010 Oct 21. PMID: 21074346. 13: Ahmad N, Warsi MH, Iqbal Z, Samim M, Ahmad FJ. Quantification of curcumin, demethoxycurcumin, and bisdemethoxycurcumin in rodent brain by UHPLC/ESI-Q-TOF- MS/MS after intra-nasal administration of curcuminoids loaded PNIPAM nanoparticles. Drug Test Anal. 2014 Mar;6(3):257-67. doi: 10.1002/dta.1472. Epub 2013 May 22. PMID: 23703969. 14: Liu Q, Wang J, Yang L, Jia Y, Kong L. A rapid and sensitive LC-MS/MS assay for the determination of berbamine in rat plasma with application to preclinical pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Jun 15;929:70-5. doi: 10.1016/j.jchromb.2013.04.007. Epub 2013 Apr 17. PMID: 23660248. 15: Fu I, Woolf EJ, Matuszewski BK. Determination of fexofenadine in human plasma using 96-well solid phase extraction and HPLC with tandem mass spectrometric detection. J Pharm Biomed Anal. 2004 Jun 29;35(4):837-46. doi: 10.1016/j.jpba.2004.02.016. PMID: 15193728. 16: Moody DE, Slawson MH, Strain EC, Laycock JD, Spanbauer AC, Foltz RL. A liquid chromatographic-electrospray ionization-tandem mass spectrometric method for determination of buprenorphine, its metabolite, norbuprenorphine, and a coformulant, naloxone, that is suitable for in vivo and in vitro metabolism studies. Anal Biochem. 2002 Jul 1;306(1):31-9. doi: 10.1006/abio.2002.5673. PMID: 12069411. 17: Moody DE, Laycock JD, Spanbauer AC, Crouch DJ, Foltz RL, Josephs JL, Amass L, Bickel WK. Determination of buprenorphine in human plasma by gas chromatography-positive ion chemical ionization mass spectrometry and liquid chromatography-tandem mass spectrometry. J Anal Toxicol. 1997 Oct;21(6):406-14. doi: 10.1093/jat/21.6.406. PMID: 9323518. 18: Tracqui A, Kintz P, Mangin P. HPLC/MS determination of buprenorphine and norbuprenorphine in biological fluids and hair samples. J Forensic Sci. 1997 Jan;42(1):111-4. PMID: 8988582. 19: Joppich-Kuhn R, Hänggi R, Sagelsdorff P, Smith AE, Weideli HJ, Joppich M. Determination of dichlorobenzidine-hemoglobin adducts by GC/MS-NCI. Int Arch Occup Environ Health. 1997;69(4):240-6. doi: 10.1007/s004200050142. PMID: 9137997. 20: Fletcher RA, Dobbins RA, Chang HC. Mass spectrometry of particles formed in a deuterated ethene diffusion flame. Anal Chem. 1998 Jul 1;70(13):2745-9. doi: 10.1021/ac971293q. PMID: 21644789.