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MedKoo Cat#: 462703 | Name: TY 10957

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TY 10957 is a biochemical that is also a stable analogue of prostacyclin.

Chemical Structure

TY 10957
TY 10957
CAS#117028-28-1

Theoretical Analysis

MedKoo Cat#: 462703

Name: TY 10957

CAS#: 117028-28-1

Chemical Formula: C25H34O6

Exact Mass: 430.2355

Molecular Weight: 430.54

Elemental Analysis: C, 69.74; H, 7.96; O, 22.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
TY-10957;
IUPAC/Chemical Name
2-(2-((1R,2R,3aS,7aS)-2-hydroxy-1-((R,E)-3-hydroxy-4-methyl-4-phenoxypent-1-en-1-yl)-2,3,3a,6,7,7a-hexahydro-1H-inden-5-yl)ethoxy)acetic acid
InChi Key
MYKBQVAHYUHFQI-ANAHPKEFSA-N
InChi Code
InChI=1S/C25H34O6/c1-25(2,31-19-6-4-3-5-7-19)23(27)11-10-21-20-9-8-17(12-13-30-16-24(28)29)14-18(20)15-22(21)26/h3-7,10-11,14,18,20-23,26-27H,8-9,12-13,15-16H2,1-2H3,(H,28,29)/b11-10+/t18-,20-,21+,22+,23+/m0/s1
SMILES Code
CC(Oc1ccccc1)([C@@H](/C=C/[C@H]2[C@@H](C[C@@H]3C=C(CC[C@H]23)CCOCC(O)=O)O)O)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 430.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Okabe S, Takeuchi K, Niida H, Takinami Y. Effects of TY-10957, a stable PGI2 derivative, on gastroduodenal lesions and secretory responses in the rat. Digestion. 1990;45(2):61-71. doi: 10.1159/000200225. PMID: 2112498. 2: Takeuchi K, Sugamoto S, Suzuki K, Kawauchi S, Furukawa O. Effects of endothelin-1 on duodenal bicarbonate secretion and mucosal integrity in rats. Chin J Physiol. 1999 Sep 30;42(3):129-35. PMID: 10707886. 3: Mauri L, Cox D, Hermiller J, Massaro J, Wahr J, Tay SW, Jonas M, Popma JJ, Pavliska J, Wahr D, Rogers C. The PROXIMAL trial: proximal protection during saphenous vein graft intervention using the Proxis Embolic Protection System: a randomized, prospective, multicenter clinical trial. J Am Coll Cardiol. 2007 Oct 9;50(15):1442-9. doi: 10.1016/j.jacc.2007.06.039. Epub 2007 Sep 24. PMID: 17919563.