Synonym
ANR-94; ANR94; ANR 94
IUPAC/Chemical Name
8-Ethoxy-9-ethyl-9H-purin-6-amine
InChi Key
QUGDTMONBLMLLD-UHFFFAOYSA-N
InChi Code
InChI=1S/C9H13N5O/c1-3-14-8-6(7(10)11-5-12-8)13-9(14)15-4-2/h5H,3-4H2,1-2H3,(H2,10,11,12)
SMILES Code
CCN2C1=NC=NC(N)=C1N=C2OCC
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
207.24
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Pinna A, Volpini R, Cristalli G, Morelli M. New adenosine A2A receptor
antagonists: actions on Parkinson's disease models. Eur J Pharmacol. 2005 Apr
11;512(2-3):157-64. doi: 10.1016/j.ejphar.2005.01.057. PMID: 15840400.
2: Pinna A, Tronci E, Schintu N, Simola N, Volpini R, Pontis S, Cristalli G,
Morelli M. A new ethyladenine antagonist of adenosine A(2A) receptors:
behavioral and biochemical characterization as an antiparkinsonian drug.
Neuropharmacology. 2010 Mar;58(3):613-23. doi: 10.1016/j.neuropharm.2009.11.012.
Epub 2009 Dec 4. PMID: 19951715.
3: Micioni Di Bonaventura MV, Cifani C, Lambertucci C, Volpini R, Cristalli G,
Froldi R, Massi M. Effects of A₂A adenosine receptor blockade or stimulation on
alcohol intake in alcohol-preferring rats. Psychopharmacology (Berl). 2012
Feb;219(4):945-57. doi: 10.1007/s00213-011-2430-1. Epub 2011 Aug 11. PMID:
21833502.
4: Marucci G, Finaurini S, Buccioni M, Lammi C, Kandhavelu M, Volpini R,
Ricciutelli M, Angeli P, Commandeur JN, Cristalli G. In vitro metabolism studies
of new adenosine A 2A receptor antagonists. Drug Metab Lett. 2008
Dec;2(4):301-7. doi: 10.2174/187231208786734076. PMID: 19356109.
5: Micioni Di Bonaventura MV, Pucci M, Giusepponi ME, Romano A, Lambertucci C,
Volpini R, Micioni Di Bonaventura E, Gaetani S, Maccarrone M, D'Addario C,
Cifani C. Regulation of adenosine A2A receptor gene expression in a
model of binge eating in the amygdaloid complex of female rats. J
Psychopharmacol. 2019 Dec;33(12):1550-1561. doi: 10.1177/0269881119845798. Epub
2019 Jun 4. PMID: 31161847.