MedKoo Cat#: 574333 | Name: ANR-94
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ANR-94 is an adenosine A2A receptor (AA2AR) antagonist that displays activity in the treatment of Parkinson's disease in vivo, improves parkinsonian motor deficits and tremors, and exhibits neuroprotective and anti-inflammatory effects.

Chemical Structure

ANR-94
ANR-94
CAS# 634924-89-3

Theoretical Analysis

MedKoo Cat#: 574333

Name: ANR-94

CAS#: 634924-89-3

Chemical Formula: C9H13N5O

Exact Mass: 207.1120

Molecular Weight: 207.24

Elemental Analysis: C, 52.16; H, 6.32; N, 33.79; O, 7.72

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
200mg USD 1,950.00 2 Weeks
500mg USD 2,850.00 2 Weeks
1g USD 4,250.00 2 Weeks
2g USD 6,450.00 2 Weeks
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Related CAS #
No Data
Synonym
ANR-94; ANR94; ANR 94
IUPAC/Chemical Name
8-Ethoxy-9-ethyl-9H-purin-6-amine
InChi Key
QUGDTMONBLMLLD-UHFFFAOYSA-N
InChi Code
InChI=1S/C9H13N5O/c1-3-14-8-6(7(10)11-5-12-8)13-9(14)15-4-2/h5H,3-4H2,1-2H3,(H2,10,11,12)
SMILES Code
CCN2C1=NC=NC(N)=C1N=C2OCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 207.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pinna A, Volpini R, Cristalli G, Morelli M. New adenosine A2A receptor antagonists: actions on Parkinson's disease models. Eur J Pharmacol. 2005 Apr 11;512(2-3):157-64. doi: 10.1016/j.ejphar.2005.01.057. PMID: 15840400. 2: Pinna A, Tronci E, Schintu N, Simola N, Volpini R, Pontis S, Cristalli G, Morelli M. A new ethyladenine antagonist of adenosine A(2A) receptors: behavioral and biochemical characterization as an antiparkinsonian drug. Neuropharmacology. 2010 Mar;58(3):613-23. doi: 10.1016/j.neuropharm.2009.11.012. Epub 2009 Dec 4. PMID: 19951715. 3: Micioni Di Bonaventura MV, Cifani C, Lambertucci C, Volpini R, Cristalli G, Froldi R, Massi M. Effects of A₂A adenosine receptor blockade or stimulation on alcohol intake in alcohol-preferring rats. Psychopharmacology (Berl). 2012 Feb;219(4):945-57. doi: 10.1007/s00213-011-2430-1. Epub 2011 Aug 11. PMID: 21833502. 4: Marucci G, Finaurini S, Buccioni M, Lammi C, Kandhavelu M, Volpini R, Ricciutelli M, Angeli P, Commandeur JN, Cristalli G. In vitro metabolism studies of new adenosine A 2A receptor antagonists. Drug Metab Lett. 2008 Dec;2(4):301-7. doi: 10.2174/187231208786734076. PMID: 19356109. 5: Micioni Di Bonaventura MV, Pucci M, Giusepponi ME, Romano A, Lambertucci C, Volpini R, Micioni Di Bonaventura E, Gaetani S, Maccarrone M, D'Addario C, Cifani C. Regulation of adenosine A2A receptor gene expression in a model of binge eating in the amygdaloid complex of female rats. J Psychopharmacol. 2019 Dec;33(12):1550-1561. doi: 10.1177/0269881119845798. Epub 2019 Jun 4. PMID: 31161847.