MedKoo Cat#: 534592 | Name: Loxoprofen sodium hydrate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Loxoprofen sodium hydrate is a bioactive chemical.

Chemical Structure

Loxoprofen sodium hydrate
Loxoprofen sodium hydrate
CAS#226721-96-6 (Hydrate)

Theoretical Analysis

MedKoo Cat#: 534592

Name: Loxoprofen sodium hydrate

CAS#: 226721-96-6 (Hydrate)

Chemical Formula: C15H21NaO5

Exact Mass: 0.0000

Molecular Weight: 304.32

Elemental Analysis: C, 59.20; H, 6.96; Na, 7.55; O, 26.29

Price and Availability

Size Price Availability Quantity
5g USD 350.00 2 Weeks
25g USD 750.00 2 Weeks
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Related CAS #
80382-23-6 (sodium) 68767-14-6 (free acid) 226721-96-6 (sodium hydrate)
Synonym
Loxoprofen sodium hydrate; Lobu; Loxonin; Oxeno
IUPAC/Chemical Name
Benzeneacetic acid, alpha-methyl-4-((2-oxocyclopentyl)methyl)-, sodium salt, hydrate (1:1:2)
InChi Key
BAZQYVYVKYOAGO-UHFFFAOYSA-M
InChi Code
InChI=1S/C15H18O3.Na.2H2O/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16;;;/h5-8,10,13H,2-4,9H2,1H3,(H,17,18);;2*1H2/q;+1;;/p-1
SMILES Code
O=C([O-])C(C)C1=CC=C(CC2C(CCC2)=O)C=C1.[H]O[H].[H]O[H].[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 304.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nakai N, Katoh N. A case of fixed drug eruption caused by loxoprofen sodium hydrate. Allergol Int. 2015 Oct;64(4):377-8. doi: 10.1016/j.alit.2015.04.007. Epub 2015 May 15. PMID: 26433535. 2: Kamiyoshihara M, Nagashima T, Ibe T, Atsumi J, Shimizu K, Takeyoshi I. Is epidural analgesia necessary after video-assisted thoracoscopic lobectomy? Asian Cardiovasc Thorac Ann. 2010 Oct;18(5):464-8. doi: 10.1177/0218492310381817. PMID: 20947601. 3: Ohshima S, Ieda M, Yamamoto M, Kobayashi D. [Quantitative evaluation method of the informational value of initial symptoms based on Bayesian theory]. Yakugaku Zasshi. 2012;132(6):763-8. Japanese. doi: 10.1248/yakushi.132.763. PMID: 22687735. 4: Yamane T, Ishii T, Umeda A, Takeda A, Shimao H, Morisane T. Giant Gastric Antral Ulcer Developing After Short-Term NSAID Administration. Gastroenterology Res. 2011 Dec;4(6):294-296. doi: 10.4021/gr382w. Epub 2011 Nov 20. PMID: 27957032; PMCID: PMC5139870. 5: Nomura S, Shimakawa S, Fukui M, Tanabe T, Tamai H. Lamotrigine for intractable migraine-like headaches in Sturge-Weber syndrome. Brain Dev. 2014 May;36(5):399-401. doi: 10.1016/j.braindev.2013.06.009. Epub 2013 Jul 19. PMID: 23877022.