MedKoo Cat#: 555759 | Name: PDM-2
Featured New

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PDM-2 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor (AhR) antagonist, with a Ki of 1.2 nM.2 PDM-2 is inactive as a ligand for the estrogen receptor even at 100 µM.

Chemical Structure

PDM-2
PDM-2
CAS#688348-25-6

Theoretical Analysis

MedKoo Cat#: 555759

Name: PDM-2

CAS#: 688348-25-6

Chemical Formula: C14H9Cl3

Exact Mass: 281.9770

Molecular Weight: 283.58

Elemental Analysis: C, 59.30; H, 3.20; Cl, 37.50

Price and Availability

Size Price Availability Quantity
100mg USD 550.00 2 Weeks
200mg USD 950.00 2 Weeks
500mg USD 1,850.00 2 Weeks
1g USD 2,950.00 2 Weeks
2g USD 5,250.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
PDM-2; PDM 2; PDM2;
IUPAC/Chemical Name
1,3-dichloro-5-[(1E)-2-(4-chlorophenyl)ethenyl]-benzene
InChi Key
JMYNPQVCVQVODQ-OWOJBTEDSA-N
InChi Code
InChI=1S/C14H9Cl3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9H/b2-1+
SMILES Code
ClC1=CC=C(/C=C/C2=CC(Cl)=CC(Cl)=C2)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 283.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Denison, M.S., and Nagy, S.R. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol. 43, 309-334 (2003). 2. de Medina, P., Casper, R., Savouret, J.-F., et al. Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators. J. Med. Chem. 48(1), 287-291 (2005).