Rociclovir | CAS#108436-80-2

MedKoo Cat#: 330035 | Name: Rociclovir

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Rociclovir, also known as HOE 602, is an antiviral drug and a 6-deoxy acyclic purine nucleoside derivative, demonstrates activity against HSV-1 in mice. Rociclovir is a prodrug of ganciclovir.

Chemical Structure

Rociclovir

CAS#108436-80-2

Theoretical Analysis

MedKoo Cat#: 330035

Name: Rociclovir

CAS#: 108436-80-2

Chemical Formula: C15H25N5O3

Exact Mass: 323.1957

Molecular Weight: 323.40

Elemental Analysis: C, 55.71; H, 7.79; N, 21.66; O, 14.84

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

HOE 602; HOE-602l; HOE602l; Rociclovir

IUPAC/Chemical Name

9-[[2-(1-Methylethoxy)-1-[(1-methylethoxy)methyl]ethoxy]methyl]-9H-purin-2-amine

InChi Key

FBHWXSOQXQBXER-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H25N5O3/c1-10(2)21-6-12(7-22-11(3)4)23-9-20-8-18-13-5-17-15(16)19-14(13)20/h5,8,10-12H,6-7,9H2,1-4H3,(H2,16,17,19)

SMILES Code

NC1=NC=C2N=CN(COC(COC(C)C)COC(C)C)C2=N1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 323.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Winkler I, Winkelmann E, Scholl T, Rösner M, Jähne G, Helsberg M. Antiviral activity and pharmacokinetics of HOE 602, an acyclic nucleoside, in animal models. Antiviral Res. 1990 Aug;14(2):61-73. doi: 10.1016/0166-3542(90)90044-8. PMID: 2177317. 2: Winkelmann E, Winkler I, Rolly H, Rösner M, Jähne G. New prodrugs of acyclic nucleosides with antiviral activity. Arzneimittelforschung. 1988 Nov;38(11):1545-8. PMID: 3265058.