MedKoo Cat#: 533675 | Name: JR14a
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

JR14a is a novel potent and selective antagonist of human Complement C3a receptor.

Chemical Structure

JR14a
JR14a
CAS#2411440-41-8 (free base)

Theoretical Analysis

MedKoo Cat#: 533675

Name: JR14a

CAS#: 2411440-41-8 (free base)

Chemical Formula: C25H26Cl2N4O3S

Exact Mass: 532.1103

Molecular Weight: 533.47

Elemental Analysis: C, 56.29; H, 4.91; Cl, 13.29; N, 10.50; O, 9.00; S, 6.01

Price and Availability

Size Price Availability Quantity
25mg USD 750.00 2 Weeks
50mg USD 1,250.00 2 Weeks
100mg USD 1,950.00 2 Weeks
1g USD 4,250.00 2 Weeks
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Related CAS #
2417323-15-8 (TFA) 2411440-41-8 (free base)
Synonym
JR14a; JR-14a; JR 14a
IUPAC/Chemical Name
(5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-L-arginine
InChi Key
OHRIKWUZKGNQKQ-IBGZPJMESA-N
InChi Code
InChI=1S/C25H26Cl2N4O3S/c1-14-13-20(21(15-4-8-17(26)9-5-15)16-6-10-18(27)11-7-16)35-22(14)23(32)31-19(24(33)34)3-2-12-30-25(28)29/h4-11,13,19,21H,2-3,12H2,1H3,(H,31,32)(H,33,34)(H4,28,29,30)/t19-/m0/s1
SMILES Code
N=C(N)NCCC[C@@H](C(O)=O)NC(C1=C(C)C=C(C(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3)S1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 533.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL