Synonym
Y 19995; Y19995; Y-19995
IUPAC/Chemical Name
Methanone, (4-(2-(dimethylamino)-1-methylethoxy)phenyl)(2-(2-(dimethylamino)-1-methylethoxy)-3-pyridinyl)-, (Z)-2-butenedioate (1:2)
InChi Key
ZOXYGRVFSDRYOS-SPIKMXEPSA-N
InChi Code
InChI=1S/C22H31N3O3.2C4H4O4/c1-16(14-24(3)4)27-19-11-9-18(10-12-19)21(26)20-8-7-13-23-22(20)28-17(2)15-25(5)6;2*5-3(6)1-2-4(7)8/h7-13,16-17H,14-15H2,1-6H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
SMILES Code
O=C(C1=CC=C(OC(C)CN(C)C)C=C1)C2=CC=CN=C2OC(C)CN(C)C.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
617.65
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Tsuru S, Shinomiya N, Nomoto K. Depression of early protection against influenza virus infection by cyclophosphamide and its restoration by Y-19995 [2,4'-bis(1-methyl-2-dimethyl-aminoethoxyl)-3-benzoylpyridine dimaleate]. Nat Immun Cell Growth Regul. 1991;10(1):1-11. PubMed PMID: 2057018.
2: Fujisawa H, Tsuru S, Taniguchi M, Nomoto K. Enhancement of host defence by Y-19995 (2,4'-bis(1-methyl-2-dimethyl-aminoethoxyl)-3-benzoylpyridine dimaleate), a novel synthetic compound. II. Activation of phagocytic cell functions. J Clin Lab Immunol. 1987 Dec;24(4):177-81. PubMed PMID: 3502347.
3: Fujisawa H, Tsuru S, Hisatome M, Goto K, Oe T, Okumoto T, Taniguchi M, Nomoto K. Enhancement of host defence by Y-19995 (2,4'-bis(1-methyl-2-dimethyl-aminoethoxyl)-3-benzoylpyridine dimaleate), a novel synthetic compound. I. Accelerated restoration from the leukocytopenia and augmented protection against microbial infections in immunocompromised mice. J Clin Lab Immunol. 1987 Aug;23(4):203-8. PubMed PMID: 3312612.
