MedKoo Cat#: 574212 | Name: (–)-Cyclopenol
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(–)-Cyclopenol is a benzodiazepine alkaloid fungal metabolite that inhibits protein tyrosine phosphatase 1B (PTP1B).

Chemical Structure

(–)-Cyclopenol
(–)-Cyclopenol
CAS#20007-85-6

Theoretical Analysis

MedKoo Cat#: 574212

Name: (–)-Cyclopenol

CAS#: 20007-85-6

Chemical Formula: C17H14N2O4

Exact Mass: 310.0954

Molecular Weight: 310.31

Elemental Analysis: C, 65.80; H, 4.55; N, 9.03; O, 20.62

Price and Availability

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1mg USD 450.00 2 Weeks
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Related CAS #
No Data
Synonym
(–)-Cyclopenol; NSC 604990; NSC604990; NSC-604990;
IUPAC/Chemical Name
(2'S,3'R)-3'-(3-hydroxyphenyl)-4-methyl-spiro[3H-1,4-benzodiazepine-3,2'-oxirane]-2,5(1H,4H)-dione
InChi Key
BDDNYDPRCCDQQJ-PBHICJAKSA-N
InChi Code
InChI=1S/C17H14N2O4/c1-19-15(21)12-7-2-3-8-13(12)18-16(22)17(19)14(23-17)10-5-4-6-11(20)9-10/h2-9,14,20H,1H3,(H,18,22)/t14-,17+/m1/s1
SMILES Code
O=C1[C@@]2([C@@H](C3=CC=CC(O)=C3)O2)N(C)C(C(C=CC=C4)=C4N1)=O
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 310.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Mohammed, Y.S., and Luckner, M. The structure of cyclopenin and cyclopenol, metabolic products from penicillium cyclopium westling and penicillium viridicatum westling. Tetrahedron Lett. 4(28), 1953-1958 (1963). 2. Sohn, J.H., Lee, Y.-R., Lee, D.-S., et al. PTP1B inhibitory secondary metabolites from marine-derived fungal strains Penicillium spp. and Eurotium sp. J. Microbiol. Biotechnol. 23(9), 1206-1211 (2013).