MS48107 is a novel positive allosteric modulator (PAM) of G protein-coupled receptor 68 (GPR68), demonstrating high selectivity over closely related proton GPCRs and 48 common drug targets, and being bioavailable and brain-penetrant in mice.
MedKoo Cat#: 533286
Name: MS48107
CAS#: 2375070-79-2
Chemical Formula: C23H20FN5O2
Exact Mass: 417.1601
Molecular Weight: 417.44
Elemental Analysis: C, 66.18; H, 4.83; F, 4.55; N, 16.78; O, 7.67
The following data is based on the product molecular weight 417.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
