ProteaseMAX | CAS#1092970-16-5 | Cleavable detergent

MedKoo Cat#: 465643 | Name: ProteaseMAX

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ProteaseMAX is sodium 3-((1-(furan-2-yl)undecyloxy)carbonylamino)propane-1-sulfonate. This cleavable detergent is sensitive to heat and acid and is degraded during a typical trypsin digestion into the uncharged lipophilic compound 1-(furan-2-yl)undecan-1-ol and the zwitterionic 3-aminopropane-1-sulfonic acid (homotaurine), which can be removed by C18 solid phase extraction during sample work-up.

Chemical Structure

ProteaseMAX

CAS#1092970-16-5 (sodium)

Theoretical Analysis

MedKoo Cat#: 465643

Name: ProteaseMAX

CAS#: 1092970-16-5 (sodium)

Chemical Formula: C19H32NNaO6S

Exact Mass: 425.1848

Molecular Weight: 425.52

Elemental Analysis: C, 53.63; H, 7.58; N, 3.29; Na, 5.40; O, 22.56; S, 7.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

1092970-16-5 (sodium) 1093059-72-3 (free acid)

Synonym

ProteaseMAX; Protease MAX; Protease-MAX;

IUPAC/Chemical Name

sodium 3-((((1-(furan-2-yl)undecyl)oxy)carbonyl)amino)propane-1-sulfonate

InChi Key

DBQVWUNRROZECZ-UHFFFAOYSA-M

InChi Code

InChI=1S/C19H33NO6S.Na/c1-2-3-4-5-6-7-8-9-12-18(17-13-10-15-25-17)26-19(21)20-14-11-16-27(22,23)24;/h10,13,15,18H,2-9,11-12,14,16H2,1H3,(H,20,21)(H,22,23,24);/q;+1/p-1

SMILES Code

O=S(CCCNC(OC(C1=CC=CO1)CCCCCCCCCC)=O)([O-])=O.[Na+]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 425.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Novikova SE, Vakhrushev IV, Tsvetkova AV, Shushkova NA, Farafonova TE, Yarygin KN, Zgoda VG. Proteomika transkriptsionnykh faktorov: identifikatsiia pula reguliatornykh belkov, spetsifichnykh dlia kletok linii HL-60 [Proteomics of transcription factors: identification of pool of HL-60 cell line-specific regulatory proteins]. Biomed Khim. 2019 Jun;65(4):294-305. Russian. doi: 10.18097/PBMC20196504294. PMID: 31436170. 2: Ji Y, Liu M, Bachschmid MM, Costello CE, Lin C. Surfactant-Induced Artifacts during Proteomic Sample Preparation. Anal Chem. 2015 Jun 2;87(11):5500-4. doi: 10.1021/acs.analchem.5b00249. Epub 2015 May 20. PMID: 25945600; PMCID: PMC4574305. 3: Lo A, Tang Y, Chen L, Li L. Automation of dimethylation after guanidination labeling chemistry and its compatibility with common buffers and surfactants for mass spectrometry-based shotgun quantitative proteome analysis. Anal Chim Acta. 2013 Jul 25;788:81-8. doi: 10.1016/j.aca.2013.05.060. Epub 2013 Jun 10. PMID: 23845485.