JS-11 is a novel hNPR1 antagonist, inhibiting receptor activity through a noncompetitive mechanism, inhibiting itching in a mouse model of contact dermatitis.
MedKoo Cat#: 533239
Name: JS-11
CAS#: 1394592-04-1
Chemical Formula: C23H28N4O3
Exact Mass: 408.2161
Molecular Weight: 408.50
Elemental Analysis: C, 67.63; H, 6.91; N, 13.72; O, 11.75
The following data is based on the product molecular weight 408.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
