SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases.
MedKoo Cat#: 533185
Name: SGC6870
CAS#: 2561471-27-8 (R-isomer)
Chemical Formula: C23H21BrN2O2S
Exact Mass: 468.0507
Molecular Weight: 469.40
Elemental Analysis: C, 58.85; H, 4.51; Br, 17.02; N, 5.97; O, 6.82; S, 6.83
| Solvent | mg/mL | mM | comments | |
|---|---|---|---|---|
| Solubility | ||||
| Soluble in DMSO | 0.0 | 100.00 |
The following data is based on the product molecular weight 469.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
