MedKoo Cat#: 574067 | Name: BAY 293 Negative Control
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BAY 293 Negative Control is a negative control for BAY-293.

Chemical Structure

BAY 293 Negative Control
BAY 293 Negative Control
CAS#2244904-69-4 (S-isomer)

Theoretical Analysis

MedKoo Cat#: 574067

Name: BAY 293 Negative Control

CAS#: 2244904-69-4 (S-isomer)

Chemical Formula: C25H28N4O2S

Exact Mass: 448.1933

Molecular Weight: 448.58

Elemental Analysis: C, 66.94; H, 6.29; N, 12.49; O, 7.13; S, 7.15

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
25mg USD 950.00 2 Weeks
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Related CAS #
Synonym
BAY 293 Negative Control; BAY-293 Negative Control; BAY293 Negative Control; BAY293 (S)-enantiomer
IUPAC/Chemical Name
(S)-6,7-Dimethoxy-2-methyl-N-[1-[4-[2-[(methylamino)methyl]phenyl]thiophene-2-yl]ethyl]quinazolin-4-amine
InChi Key
WEGLOYDTDILXDA-HNNXBMFYSA-N
InChi Code
InChI=1S/C25H28N4O2S/c1-15(24-10-18(14-32-24)19-9-7-6-8-17(19)13-26-3)27-25-20-11-22(30-4)23(31-5)12-21(20)28-16(2)29-25/h6-12,14-15,26H,13H2,1-5H3,(H,27,28,29)/t15-/m0/s1
SMILES Code
CNCC1=C(C2=CSC([C@@H](NC3=NC(C)=NC4=C3C=C(C(OC)=C4)OC)C)=C2)C=CC=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 448.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Hillig et al (2019) Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction. Proc.Natl.Acad.Sci.USA. 116 2551 PMID: 30683722