Synonym
2-hATQ; 2 hATQ; 2-Hydroxyanthraquinone; 2 Hydroxyanthraquinone; 2-hydroxy-9,10-Anthraquinone; β-Hydroxyanthraquinone; β Hydroxyanthraquinone; NSC 2595; NSC2595; NSC-2595;
IUPAC/Chemical Name
2-hydroxyanthracene-9,10-dione
InChi Key
GCDBEYOJCZLKMC-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H8O3/c15-8-5-6-11-12(7-8)14(17)10-4-2-1-3-9(10)13(11)16/h1-7,15H
SMILES Code
O=C1C2=C(C=CC=C2)C(C3=CC(O)=CC=C13)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
|
Solvent |
mg/mL |
mM |
comments |
| Solubility |
| DMF |
5.0 |
22.30 |
|
| DMSO |
30.0 |
133.80 |
|
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
224.22
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Mallakin A, McConkey BJ, Miao G, McKibben B, Snieckus V, Dixon DG, Greenberg BM. Impacts of structural photomodification on the toxicity of environmental contaminants: anthracene photooxidation products. Ecotoxicol Environ Saf. 1999 Jun;43(2):204-12. doi: 10.1006/eesa.1999.1764. PMID: 10375423.
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4: Shi Y, Wang CH, Gong XG. Apoptosis-inducing effects of two anthraquinones from Hedyotis diffusa WILLD. Biol Pharm Bull. 2008 Jun;31(6):1075-8. doi: 10.1248/bpb.31.1075. PMID: 18520033.
5: Tikkanen L, Matsushima T, Natori S. Mutagenicity of anthraquinones in the Salmonella preincubation test. Mutat Res. 1983 Mar;116(3-4):297-304. doi: 10.1016/0165-1218(83)90067-8. PMID: 6339896.
6: Hilgert I, Cudlín J, Steinerová N, Vanĕk Z. Antitumour and immunosuppressive activity of hydroxyanthraquinones and their glucosides. Folia Biol (Praha). 1977;23(2):99-109. PMID: 863051.
