MedKoo Cat#: 574048 | Name: NAP-1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

NAP-1 is a compound with anesthetic activity. It increases paired-pulse inhibition in the CA1 region of the hippocampus.

Chemical Structure

NAP-1
NAP-1
CAS#131721-28-3

Theoretical Analysis

MedKoo Cat#: 574048

Name: NAP-1

CAS#: 131721-28-3

Chemical Formula: C20H18ClNO2

Exact Mass: 339.1026

Molecular Weight: 339.82

Elemental Analysis: C, 70.69; H, 5.34; Cl, 10.43; N, 4.12; O, 9.42

Price and Availability

Size Price Availability Quantity
1mg USD 205.00
5mg USD 385.00
10mg USD 625.00
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Related CAS #
No Data
Synonym
NAP-1, NAP1, NAP 1
IUPAC/Chemical Name
5-(4-chlorophenyl)-2-methyl-1-phenyl-1H-pyrrole-3-carboxylic acid, ethyl ester
InChi Key
RYNBQQWODYCGRR-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H18ClNO2/c1-3-24-20(23)18-13-19(15-9-11-16(21)12-10-15)22(14(18)2)17-7-5-4-6-8-17/h4-13H,3H2,1-2H3
SMILES Code
CC1=C(C(OCC)=O)C=C(C2=CC=C(Cl)C=C2)N1C3=CC=CC=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
NAP-1 is a compound with anesthetic activity.
In vitro activity:
TBD
In vivo activity:
TBD
Solvent mg/mL mM
Solubility
DMSO 10.0 29.43
DMF:PBS (pH 7.2) (1:2) 0.3 0.88
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 339.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1. Bertaccini, E.J., and Davies, M.F. Novel methods, compounds, and compositions for anesthesia. (2016).