MedKoo Cat#: 574045 | Name: Elaidamide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Elaidamide is a fatty acid amide that has been found in the cerebrospinal fluid (CSF) of sleep-deprived cats. It inhibits rat microsomal epoxide hydrolase. Elaidamide also inhibits porcine pancreatic and human synovial phospholipase A2 (PLA2). In vivo, Elaidamide induces physiological sleep in rats.

Chemical Structure

Elaidamide
Elaidamide
CAS#4303-70-2

Theoretical Analysis

MedKoo Cat#: 574045

Name: Elaidamide

CAS#: 4303-70-2

Chemical Formula: C18H35NO

Exact Mass: 281.2719

Molecular Weight: 281.48

Elemental Analysis: C, 76.81; H, 12.53; N, 4.98; O, 5.68

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
Elaidamide, Elaidoylamide; Elaidic Acid amide; 9-Octadecenamide; (E)-octadec-9-enamide
IUPAC/Chemical Name
(9E)-9-octadecenamide
InChi Key
FATBGEAMYMYZAF-MDZDMXLPSA-N
InChi Code
InChI=1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9+
SMILES Code
CCCCCCCC/C=C/CCCCCCCC(N)=O
Appearance
A crystalline solid
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 281.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Cravatt, B.F., Prospero-Garcia, O., Siuzdak, G., et al. Chemical characterization of a family of brain lipids that induce sleep. Science 268(5216), 1506-1509 (1995). 2. Morisseau, C., Newman, J.W., Dowdy, D.L., et al. Inhibition of microsomal epoxide hydrolases by ureas, amides, and amines. Chem. Res. Toxicol. 14(4), 409-415 (2001). 3. Jain, M.K., Ghomashchi, F., Yu, B.Z., et al. Fatty acid amides: scooting mode-based discovery of tight-binding competitive inhibitors of secreted phospholipases A2. J. Med. Chem. 35(19), 3584-3586 (1992).