LY 87130 | CAS#72877-72-6

MedKoo Cat#: 525553 | Name: LY 87130

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LY 87130 is an inhibitor of phenylethanolamine-N-methyltransferase.

Chemical Structure

LY 87130

CAS#72877-72-6

Theoretical Analysis

MedKoo Cat#: 525553

Name: LY 87130

CAS#: 72877-72-6

Chemical Formula: C12H14ClN

Exact Mass:

Molecular Weight: 207.70

Elemental Analysis: C, 69.39; H, 6.79; Cl, 17.07; N, 6.74

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

LY 87130; LY87130; LY-87130.

IUPAC/Chemical Name

2,3,4,5-Tetrahydro-1H-indeno(1,2-c)pyridine hydrochloride

InChi Key

YYDDAWDCRFXJNY-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H13N.ClH/c1-2-4-11-9(3-1)7-10-5-6-13-8-12(10)11;/h1-4,13H,5-8H2;1H

SMILES Code

[H]Cl.C12=C(CC3=C2C=CC=C3)CCNC1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 207.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Routledge C, Marsden CA. Comparison of the effects of selected drugs on the release of hypothalamic adrenaline and noradrenaline measured in vivo. Brain Res. 1987 Nov 17;426(1):103-11. PubMed PMID: 2446707. 2: Routledge C, Marsden CA. Adrenaline in the CNS: in vivo evidence for a functional pathway innervating the hypothalamus. Neuropharmacology. 1987 Jul;26(7B):823-30. Review. PubMed PMID: 2889157. 3: Coen CW, Simonyi A, Fekete MI. Effect of phenylethanolamine N-methyltransferase inhibition on serum concentrations of luteinizing hormone, follicle stimulating hormone and prolactin in pro-oestrous and ovariectomized rats. Brain Res. 1985 Sep 23;343(2):383-7. PubMed PMID: 3931859. 4: Fuller RW, Molloy BB, Hemrick SK, Perry KW. Inhibition of rat brain norepinephrine N-methyltransferase by 2,3,4,5-tetrahydro-1H-indeno [1,2-c]pyridine hydrochloride (LY87130). Brain Res. 1980 May 19;190(1):215-23. PubMed PMID: 7378735.