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MedKoo Cat#: 533052 | Name: mcMMAD
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

mcMMAD is a novel mc (maleimidocaproyl) linker plus MMAD (Monomethylauristatin D) to be used for prepare antibodies conjugates via cysteine-capped mechanism.

Chemical Structure

mcMMAD
mcMMAD
CAS#1401963-15-2

Theoretical Analysis

MedKoo Cat#: 533052

Name: mcMMAD

CAS#: 1401963-15-2

Chemical Formula: C51H77N7O9S

Exact Mass: 963.5503

Molecular Weight: 964.28

Elemental Analysis: C, 63.53; H, 8.05; N, 10.17; O, 14.93; S, 3.32

Price and Availability

Size Price Availability Quantity
5mg USD 1,350.00 2 Weeks
10mg USD 2,350.00 2 Weeks
25mg USD 4,350.00 2 Weeks
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Related CAS #
No Data
Synonym
mcMMAD; Mc-Monomethylauristatin D; maleimidocaproy Monomethylauristatin D
IUPAC/Chemical Name
6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((R)-1-(((R)-1-(((3R,4S,5R)-3-methoxy-1-((R)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((S)-2-phenyl-1-(thiazol-2-yl)ethyl)amino)propyl)pyrrolidin-1-yl)-5-methyl-1-oxoheptan-4-yl)(methyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)-N-methylhexanamide
InChi Key
OZUQLKHIIRUJRZ-FYCUXIKQSA-N
InChi Code
InChI=1S/C51H77N7O9S/c1-12-34(6)46(56(9)51(65)44(32(2)3)54-49(64)45(33(4)5)55(8)40(59)23-17-14-18-27-58-41(60)24-25-42(58)61)39(66-10)31-43(62)57-28-19-22-38(57)47(67-11)35(7)48(63)53-37(50-52-26-29-68-50)30-36-20-15-13-16-21-36/h13,15-16,20-21,24-26,29,32-35,37-39,44-47H,12,14,17-19,22-23,27-28,30-31H2,1-11H3,(H,53,63)(H,54,64)/t34-,35-,37+,38-,39-,44-,45-,46+,47-/m1/s1
SMILES Code
O=C(N([C@H](C(C)C)C(N[C@H](C(C)C)C(N([C@@H]([C@H](C)CC)[C@H](OC)CC(N1[C@@H]([C@H](OC)[C@@H](C)C(N[C@H](C2=NC=CS2)CC3=CC=CC=C3)=O)CCC1)=O)C)=O)=O)C)CCCCCN4C(C=CC4=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 964.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL