KRA-533 is a novel KRAS Agonist, binding the GTP/GDP-binding pocket of KRAS, preventing the cleavage of GTP into GDP, leading to the accumulation of GTP-KRAS, an active form of KRAS.
MedKoo Cat#: 532907
Name: KRA-533
CAS#: 10161-87-2
Chemical Formula: C13H16BrNO3
Exact Mass: 313.0314
Molecular Weight: 314.18
Elemental Analysis: C, 49.70; H, 5.13; Br, 25.43; N, 4.46; O, 15.28
The following data is based on the product molecular weight 314.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
