Isoproterenone is a synthetic beta-adrenergic agonist that primarily acts on beta-1 and beta-2 receptors, which are involved in regulating heart rate, bronchial dilation, and other physiological processes. It works by stimulating these receptors, leading to increased heart rate, improved blood flow, and bronchial dilation, making it useful in treating conditions like asthma, chronic obstructive pulmonary disease (COPD), and heart block. The mechanism of isoproterenone involves the activation of adenylate cyclase, increasing cyclic AMP levels and triggering a cascade of events that enhance cardiovascular and respiratory function. It is commonly used in both clinical settings for acute cardiac and respiratory conditions and in research for studying adrenergic receptor signaling.
MedKoo Cat#: 145895
Name: Isoproterenone
CAS#: 121-28-8
Chemical Formula: C11H15NO3
Exact Mass: 209.1100
Molecular Weight: 209.25
Elemental Analysis: C, 63.14; H, 7.23; N, 6.69; O, 22.94
The following data is based on the product molecular weight 209.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
