GUN35758, also known as 4'-Carboxybenzo-18C6, is a novel transthyretin (ttr) amyloidogenesis inhibitor, stabilizing the ttr tetramer by binding to the allosteric sites on the molecular surface of the ttr tetramer. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 565667
Name: GUN35758
CAS#: 60835-75-8
Chemical Formula: C17H24O8
Exact Mass: 356.1471
Molecular Weight: 356.37
Elemental Analysis: C, 57.30; H, 6.79; O, 35.92
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| Soluble in DMSO | 0.0 | 0.00 |
The following data is based on the product molecular weight 356.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
